Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
Stephen Padilla, 4 days ago
A wearable, hermetically sealed high-precision vibration sensor enables simultaneous monitoring of multiple health factors associated with the cardiopulmonary system, including heart and respiratory rates, heart sounds, lung sounds, and body motion and position of an individual, a study shows.
Tristan Manalac, 14 Feb 2020
The use of e-cigarettes with flavoured juices for weight-related reasons appears to be common among adolescents, according to a new study.
Roshini Claire Anthony, 03 Feb 2020

The emergence of a novel coronavirus (preliminarily referred to as 2019-nCoV) has taken hold of public attention in the last month. MIMS Doctor speaks to Professor Dale Fisher, a senior consultant at the Division of Infectious Diseases, National University Hospital, Singapore, to get a better picture of the situation and steps being undertaken in Singapore to prevent spread of the virus.

Mortality high among ECMO patients requiring emergency laparotomy

30 Jun 2019

While survival to discharge is possible, mortality is high among patients on extracorporeal membrane oxygenation (ECMO) needing emergency laparotomy, reports a new study.

Researchers conducted a single-centre, retrospective, observational cohort study including 355 ECMO patients. All participants needed to undergo laparotomy while attached to the machine. Study outcomes included the prevalence of emergency laparotomy, mortality risk, acute mortality rate and survival to discharge, among others.

Of the participants, 13 required laparotomies (mean age, 48.6±12.5 years; 30.8 percent female) while 342 (mean age, 44.8±14.1 years; 43.6 percent female) did not, resulting in a prevalence rate of 3.7 percent.

All patients survived laparotomy, while five died during the overall ECMO duration. Of the six patients who were successfully decannulated, an additional two died. The overall mortality rate was 69 percent. Four patients survived to hospital discharge.

 Multivariable logistic regression analysis yielded a final model with five independent variables: age, laparotomy, Acute Physiology and Chronic Health Evaluation score, Sequential Organ Failure Assessment (SOFA) score upon admission, and maximum SOFA score. This model demonstrated a good ability to distinguish between those who did and did not survive to discharge (p<0.001).

The final model yielded a sensitivity of 95.6 percent and a positive predictive value of 81.5 percent. It was able to correctly classify 79.9 percent of cases and could account for 15.2–23.1 percent of the variance in survival to discharge.

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Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
Stephen Padilla, 4 days ago
A wearable, hermetically sealed high-precision vibration sensor enables simultaneous monitoring of multiple health factors associated with the cardiopulmonary system, including heart and respiratory rates, heart sounds, lung sounds, and body motion and position of an individual, a study shows.
Tristan Manalac, 14 Feb 2020
The use of e-cigarettes with flavoured juices for weight-related reasons appears to be common among adolescents, according to a new study.
Roshini Claire Anthony, 03 Feb 2020

The emergence of a novel coronavirus (preliminarily referred to as 2019-nCoV) has taken hold of public attention in the last month. MIMS Doctor speaks to Professor Dale Fisher, a senior consultant at the Division of Infectious Diseases, National University Hospital, Singapore, to get a better picture of the situation and steps being undertaken in Singapore to prevent spread of the virus.