Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, Yesterday

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 2 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
Stephen Padilla, 12 Sep 2019
Overweight and obesity show an inverse relationship with acne in a dose-dependent manner in young adults, according to a recent study. This suggests that the metabolically active adipose tissue plays a protective role in acne.

More recent frailty assessments predict mortality better in seniors

29 Jul 2019

Frailty is a good predictor of mortality risk in the elderly for up to 10 years, with more recent assessments resulting in improved predictions, a recent study has found.

Researchers performed a population-based cohort study on 909 community-dwelling elderly adults (mean age, 74.4±6.2 years; 55 percent female), of whom 549 underwent frailty assessments at two time points. Frailty was measured using the frailty phenotype (FP) and frailty index (FI).

Over a 10-year follow-up period, 292 deaths were reported, yielding a 33.8-percent mortality rate. This was higher in males (40.1 percent vs 28.6 percent) and for those aged ≥75 years (vs 65–74 years; 54.3 percent vs 17.8 percent). Participants in the lowest income bracket were also more likely to die than their counterparts in the highest group (35.5 percent vs 11.6 percent).

According to FP, 18.3 percent of the participants were frail at baseline. The corresponding figure according to FI was 48.1 percent. In both scales, mortality rates grew with increasing levels of frailty.

For instance, 60.2 percent of those defined by FP as frail died by 10 years, as opposed to only 26.3 percent of nonfrail seniors. In FI, 45.1 percent of those who were frail died by 10 years, much higher than the 21.4 percent mortality rate in the nonfrail participants.

In those with a second frailty assessment, follow-up findings were a stronger predictor of mortality than baseline frailty results.

“Although frailty measurement was a significant predictor of mortality risk up to 10 years, recency of measurement was a stronger predictor,” said researchers.

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Most Read Articles
Roshini Claire Anthony, 11 Sep 2019

Beta-blockers could reduce mortality risk in patients with heart failure with reduced ejection fraction (HFrEF) and moderate or moderately-severe renal dysfunction without causing harm, according to the BB-META-HF* trial presented at ESC 2019.

Elvira Manzano, Yesterday

The US Preventive Services Task Force (USPSTF), in an update of its 2013 recommendations, called on clinicians to offer risk-reducing medications to women who are at increased risk for breast cancer but at low risk for adverse effects.

Pearl Toh, 2 days ago
The use of SGLT-2* inhibitors was not associated with a higher risk of severe or nonsevere urinary tract infections (UTIs) in patients with type 2 diabetes (T2D) compared with DPP**-4 inhibitors or GLP-1*** receptor agonists, a population-based cohort study shows.
Stephen Padilla, 12 Sep 2019
Overweight and obesity show an inverse relationship with acne in a dose-dependent manner in young adults, according to a recent study. This suggests that the metabolically active adipose tissue plays a protective role in acne.