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More recent frailty assessments predict mortality better in seniors

29 Jul 2019

Frailty is a good predictor of mortality risk in the elderly for up to 10 years, with more recent assessments resulting in improved predictions, a recent study has found.

Researchers performed a population-based cohort study on 909 community-dwelling elderly adults (mean age, 74.4±6.2 years; 55 percent female), of whom 549 underwent frailty assessments at two time points. Frailty was measured using the frailty phenotype (FP) and frailty index (FI).

Over a 10-year follow-up period, 292 deaths were reported, yielding a 33.8-percent mortality rate. This was higher in males (40.1 percent vs 28.6 percent) and for those aged ≥75 years (vs 65–74 years; 54.3 percent vs 17.8 percent). Participants in the lowest income bracket were also more likely to die than their counterparts in the highest group (35.5 percent vs 11.6 percent).

According to FP, 18.3 percent of the participants were frail at baseline. The corresponding figure according to FI was 48.1 percent. In both scales, mortality rates grew with increasing levels of frailty.

For instance, 60.2 percent of those defined by FP as frail died by 10 years, as opposed to only 26.3 percent of nonfrail seniors. In FI, 45.1 percent of those who were frail died by 10 years, much higher than the 21.4 percent mortality rate in the nonfrail participants.

In those with a second frailty assessment, follow-up findings were a stronger predictor of mortality than baseline frailty results.

“Although frailty measurement was a significant predictor of mortality risk up to 10 years, recency of measurement was a stronger predictor,” said researchers.

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Most Read Articles
6 days ago
Chest pain appears to be the principal complaint of patients hospitalized with a first myocardial infarction (MI), particularly among those in the youngest age group, a study has found.
Jairia Dela Cruz, 16 Sep 2020
In patients with heart failure with reduced ejection fraction (HFrEF) receiving angiotensin-converting-enzyme (ACE) inhibitors, high dosing confers benefits for the risk of death or hospitalization that are similar to that obtained with lower dosing, according to a systematic review and meta-analysis.
Pearl Toh, 6 days ago
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
Yesterday
Percutaneous coronary intervention (PCI), compared with coronary artery bypass grafting (CABG), in the revascularization of left main coronary artery (LMCA) disease may lead to death, myocardial infarction (MI), or stroke in patients with moderate or severe left ventricular (LV) dysfunction, reveals a study.