Most Read Articles
Audrey Abella, 07 Nov 2019
Cognitive behavioural therapy (CBT) may improve symptoms of irritable bowel syndrome (IBS), according to the follow-up results of the ACTIB* trial.
17 Nov 2019
Distance-based interventions to assist smoking cessation (SC) appear to be effective among cancer survivors, reports a recent meta-analysis.
19 Nov 2019
Women with post-traumatic stress disorder (PTSD) are at increased risk of developing thyroid dysfunction, a study reports.
06 Nov 2019
No consistent superior cost-effectiveness has been observed in either second-generation antidepressants (SGAs) or cognitive behavioural therapy (CBT) when compared to the other, according to a study.

Mood disorders tied to poor visuospatial memory performance

30 Nov 2019

Individuals with bipolar disorder and depression are likely to have lower visuospatial memory performance, which may partly be attributed to psychotropic medication use, a study has found.

The study used baseline data from the UK Biobank cohort and included 2,709 individuals with bipolar disorder and 102,931 matched controls, as well as 50,975 individuals with major depression and 105,284 matched controls.

Researchers evaluated reasoning, reaction time and memory, as well as the magnitude of the effect that was explained by potentially modifiable intermediate factors such as cardiometabolic disease and psychotropic medication.

Results for visuospatial memory performance revealed small between-group differences. Z-score differences were in the range of –0.23 to –0.17 (95 percent confidence interval [CI], –0.39 to –0.03) for the bipolar disorder group across different estimation methods, and were approximately –0.07 (95 percent CI, –0.10 to –0.03) for the major depression group.

Mediation analysis showed that one-quarter of the effect was explained by psychotropic medication in the bipolar disorder group (–0.05, 95 percent CI, –0.09 to –0.01), whereas no evidence was found via cardiometabolic disease.

The findings point to psychotropic medications as potential modifiable causes of cognitive impairment in patients with mood disorders, the researchers said.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Psychiatry - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Audrey Abella, 07 Nov 2019
Cognitive behavioural therapy (CBT) may improve symptoms of irritable bowel syndrome (IBS), according to the follow-up results of the ACTIB* trial.
17 Nov 2019
Distance-based interventions to assist smoking cessation (SC) appear to be effective among cancer survivors, reports a recent meta-analysis.
19 Nov 2019
Women with post-traumatic stress disorder (PTSD) are at increased risk of developing thyroid dysfunction, a study reports.
06 Nov 2019
No consistent superior cost-effectiveness has been observed in either second-generation antidepressants (SGAs) or cognitive behavioural therapy (CBT) when compared to the other, according to a study.