Most Read Articles
Dr Margaret Shi, 4 days ago

A guided web-based self-intervention, adapted from elements of cognitive behavioural therapy (CBT), may be effective in preventing the onset or recurrence of major depressive episodes (MDEs) in patients with persistent back pain, according to results of the recent PROD-BP study.

26 Mar 2020
In the treatment of post-traumatic stress disorder (PTSD), eye movement desensitization and reprocessing (EMDR) and trauma-focused cognitive behavioural therapy (TF-CBT) appear to be most effective at reducing symptoms and increasing remission rates as well as sustaining symptom improvements after therapy has ended, according to the results of a meta-analysis.
Stephen Padilla, 15 May 2020
Levels of depression and anxiety facilitate the relationship between disordered eating (DE) and body image dissatisfaction (BID) among psychiatric outpatients in a multicultural Asian setting, with DE potentially leading to a worse quality of life, according to a Singapore study.

Mood disorders tied to poor visuospatial memory performance

30 Nov 2019

Individuals with bipolar disorder and depression are likely to have lower visuospatial memory performance, which may partly be attributed to psychotropic medication use, a study has found.

The study used baseline data from the UK Biobank cohort and included 2,709 individuals with bipolar disorder and 102,931 matched controls, as well as 50,975 individuals with major depression and 105,284 matched controls.

Researchers evaluated reasoning, reaction time and memory, as well as the magnitude of the effect that was explained by potentially modifiable intermediate factors such as cardiometabolic disease and psychotropic medication.

Results for visuospatial memory performance revealed small between-group differences. Z-score differences were in the range of –0.23 to –0.17 (95 percent confidence interval [CI], –0.39 to –0.03) for the bipolar disorder group across different estimation methods, and were approximately –0.07 (95 percent CI, –0.10 to –0.03) for the major depression group.

Mediation analysis showed that one-quarter of the effect was explained by psychotropic medication in the bipolar disorder group (–0.05, 95 percent CI, –0.09 to –0.01), whereas no evidence was found via cardiometabolic disease.

The findings point to psychotropic medications as potential modifiable causes of cognitive impairment in patients with mood disorders, the researchers said.

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Most Read Articles
Dr Margaret Shi, 4 days ago

A guided web-based self-intervention, adapted from elements of cognitive behavioural therapy (CBT), may be effective in preventing the onset or recurrence of major depressive episodes (MDEs) in patients with persistent back pain, according to results of the recent PROD-BP study.

26 Mar 2020
In the treatment of post-traumatic stress disorder (PTSD), eye movement desensitization and reprocessing (EMDR) and trauma-focused cognitive behavioural therapy (TF-CBT) appear to be most effective at reducing symptoms and increasing remission rates as well as sustaining symptom improvements after therapy has ended, according to the results of a meta-analysis.
Stephen Padilla, 15 May 2020
Levels of depression and anxiety facilitate the relationship between disordered eating (DE) and body image dissatisfaction (BID) among psychiatric outpatients in a multicultural Asian setting, with DE potentially leading to a worse quality of life, according to a Singapore study.