Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 3 days ago
For individuals with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
3 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.

Modified low-protein formula supports adequate growth in infants

12 May 2020

Healthy term-born infants consuming a modified low-protein (mLP) formula from 1 month until 6 months of age show adequate growth comparable to those fed with a control formula, a recent study has shown.

In this double-blind, randomized controlled equivalence trial, infants were randomly assigned to receive either mLP (1.7 g protein/100 kcal; n=90) or control formula (2.1 g protein/100 kcal; n=88) from enrolment (age ≤45 days) to 6 months of age. A breastfed group served as reference (n=67). The investigators determined anthropometry and body composition at baseline, 17 weeks (including safety blood parameters) and 6 months of age.

The primary outcome of daily weight gain from baseline (mean age, 31±9 days) up to the age of 17 weeks was similar between the mLP and control formula groups (27.9 vs 28.8 g/day; difference, –0.86 g/day, 90 percent confidence interval [CI], –2.36 to 0.63). There were no differences seen in other growth parameters, body composition or adverse events.

Infants consuming mLP formula had significantly lower urea than those fed with control formula (–0.74 mmol/L, 95 percent CI, –0.97 to –0.51; p<0.001). Both formula groups, however, demonstrated significantly higher growth rates, fat mass, fat-free mass and several essential amino acids than the breastfed reference group.

“A high protein intake in early life is associated with a risk of obesity later in life,” the investigators said. “The essential amino acid requirements of formula-fed infants have been reassessed recently, enabling a reduction in total protein content and thus in protein intake.”

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Elvira Manzano, 2 days ago
Monthly injections of the PCSK9* monoclonal antibody evolocumab effectively reduced plasma LDL-cholesterol (LDL-C), often referred to as the bad cholesterol, in teenagers with heterozygous familial hypercholesterolaemia (HeFH) already taking statins, with or without ezetimibe, the HAUSER-RCT has shown.
Jairia Dela Cruz, 3 days ago
For individuals with type 2 diabetes, losing weight is everything when it comes to improving the metabolic function, and it matters little whether this is achieved by dieting or undergoing bariatric surgery, according to a small study.
Pearl Toh, 21 Sep 2020
Early and sustained treatments with simplified regimen are the key to achieving good asthma control, said experts during a presentation at the ERS 2020 Congress.
3 days ago
In patients with type 2 diabetes (T2D), postprandial hyperglycaemia and hypertriglyceridemia worsens survival outlook, finds a new study.