Most Read Articles
29 Jan 2020
Several high-density lipoprotein (HDL) functionality parameters, which are linked to HDL roles on cholesterol metabolism, endothelial protection and antioxidant/anti-inflammatory defence, contribute to an increased risk of incident acute coronary syndromes and its manifestations in individuals at high risk of cardiovascular disease, a study reports.
Jairia Dela Cruz, 3 days ago
A wearable arrhythmia detection device, the AliveCor KardiaBand (KB), demonstrates moderate accuracy for diagnosing atrial fibrillation (AF) in comparison with a 12-lead electrocardiogram (ECG), as shown in a recent study. However, combining the automated device diagnosis with the electrophysiologists (EP) interpretation of unclassified readings improves overall accuracy.
Stephen Padilla, 23 May 2019
A recent study has shown an association between regular use of glucosamine supplement to relieve osteoarthritis pain and lower risk of cardiovascular disease (CVD) events.
Pearl Toh, 10 Feb 2020
Contrary to popular concern, use of statins was not associated with a greater decline in memory or cognition in the elderly over 6 years, according to data from the observational MAS*.

Moderate/severe tricuspid regurgitation predicts survival after PMVR

22 Oct 2019

Moderate or severe tricuspid regurgitation (TR) after percutaneous mitral valve repair (PMVR) is associated with worse clinical outcomes and long-term survival, a recent study has found.

Researchers performed a retrospective observational investigation of 213 consecutive PMVR patients, who were divided into two groups according to the degree of TR: none/mild (n=129; mean age, 75.3±8.9 years; 71.3 percent male) and moderate/severe (n=84; mean age, 75.8±8.9 years; 60.7 percent male). Those in the latter group had worse functional capacity after the procedure.

The overall survival rates at 1 and 2 years after PMVR were 79.3 percent (n=169) and 63.4 percent (n=135), respectively. These figures were significantly higher in the no/mild vs moderate/severe TR groups (1 year: 85.3 percent vs 70.2 percent; p=0.011; 2 years: 68.2 percent vs 56.0 percent; p=0.025). The median survival time was 1,458 days.

Fully adjusted proportional hazards models confirmed that postprocedural TR grade was a significant and independent predictor of long-term survival (hazard ratio [HR], 2.055, 95 percent CI, 1.317–3.206; p=0.002).

Other predictive factors included a severely impaired postprocedural left ventricular systolic function (HR, 3.145, 1.199–8.250; p=0.020) and chronic kidney disease, defined either as estimated glomerular filtration rate 30–60 (HR, 1.917, 1.109–3.314; p=0.02) or <30 mL/min (HR, 3.969, 1.981–7.951; p<0.001)

“TR should be taken into account when patients undergo PMVR, including right ventricular characteristics and pulmonary pressure,” said researchers. “A closer monitoring and follow-up in patients with residual moderate to severe TR seems reasonable.”

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
29 Jan 2020
Several high-density lipoprotein (HDL) functionality parameters, which are linked to HDL roles on cholesterol metabolism, endothelial protection and antioxidant/anti-inflammatory defence, contribute to an increased risk of incident acute coronary syndromes and its manifestations in individuals at high risk of cardiovascular disease, a study reports.
Jairia Dela Cruz, 3 days ago
A wearable arrhythmia detection device, the AliveCor KardiaBand (KB), demonstrates moderate accuracy for diagnosing atrial fibrillation (AF) in comparison with a 12-lead electrocardiogram (ECG), as shown in a recent study. However, combining the automated device diagnosis with the electrophysiologists (EP) interpretation of unclassified readings improves overall accuracy.
Stephen Padilla, 23 May 2019
A recent study has shown an association between regular use of glucosamine supplement to relieve osteoarthritis pain and lower risk of cardiovascular disease (CVD) events.
Pearl Toh, 10 Feb 2020
Contrary to popular concern, use of statins was not associated with a greater decline in memory or cognition in the elderly over 6 years, according to data from the observational MAS*.