Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
18 Feb 2021
Treatment with tanezumab appears to relieve pain and improve physical function in patients with hip or knee osteoarthritis (OA), but may lead to dose-dependent increase in joint safety events as compared with nonsteroidal anti-inflammatory drug (NSAID), according to the results of a phase III safety trial.
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Mobility restrictions, social distancing help stem COVID-19 tide

2 days ago

Restricting mobility seems to be an effective approach to control the novel coronavirus disease (COVID-19) pandemic and leads to declining transmission, a recent analysis has shown. 

Data regarding COVID-19 deaths were sourced from the World Health Organization (WHO) and the European Centres for Disease Control, while data for mobility were obtained from Apple and Google, which collected movement information from mapping apps. Fifty-two countries had sufficient epidemiological and mobility data and were included in the analysis.

Overall, the median mobility across all countries was lowest on 11 March 2020, during which mobility was 63-percent lower than baseline. In turn, the virus’ effective reproduction number dropped sharply, according to statistical models. This was also true for the estimated reproduction number for deaths.

Notably, by the second half of May 2020, there was a slight decoupling of mobility and transmissibility. As movement started to gradually increase, so did transmissibility, but at a slower pace than expected.

The researchers then sought to determine mobility thresholds that could keep the virus’ reproduction number below 1.0. They found that, at least in the UK, an initial 43-percent mobility reduction would be necessary, but after considering other social distancing behaviours, the threshold could be as low as 18 percent. These values varied largely for the different countries assessed.

“We found strong evidence that the relationship between mobility and transmissibility changed over time, typically, a dampening indicating that smaller reductions in mobility can result in epidemic control likely due to other social distancing behaviours,” the researchers said.

“As many countries are re-imposing social-distancing policies, our analysis illustrates that sustainable relaxation of population-wide social-distancing measures should be undertaken very carefully and replaced with equally effective control measures, such as thorough contact-tracing,” they added.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
18 Feb 2021
Treatment with tanezumab appears to relieve pain and improve physical function in patients with hip or knee osteoarthritis (OA), but may lead to dose-dependent increase in joint safety events as compared with nonsteroidal anti-inflammatory drug (NSAID), according to the results of a phase III safety trial.
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.