Most Read Articles
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Roshini Claire Anthony, 5 days ago

Switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) did not result in worsening renal function or bone mineral density (BMD) in Asian patients with chronic hepatitis B virus (HBV) infection, according to a small real-world prospective study.

5 days ago
The standard combination therapy against paediatric migraine—consisting of a combination of parenteral medications—appears to yield moderate pain relief, which persists up to 1 week after administration, a new study has found.
Roshini Claire Anthony, 3 days ago

Critical or severe COVID-19 disease could raise the risk of negative perinatal outcomes in pregnant women, according to an observational study from the US.

Mobility restrictions, social distancing help stem COVID-19 tide

23 Feb 2021

Restricting mobility seems to be an effective approach to control the novel coronavirus disease (COVID-19) pandemic and leads to declining transmission, a recent analysis has shown. 

Data regarding COVID-19 deaths were sourced from the World Health Organization (WHO) and the European Centres for Disease Control, while data for mobility were obtained from Apple and Google, which collected movement information from mapping apps. Fifty-two countries had sufficient epidemiological and mobility data and were included in the analysis.

Overall, the median mobility across all countries was lowest on 11 March 2020, during which mobility was 63-percent lower than baseline. In turn, the virus’ effective reproduction number dropped sharply, according to statistical models. This was also true for the estimated reproduction number for deaths.

Notably, by the second half of May 2020, there was a slight decoupling of mobility and transmissibility. As movement started to gradually increase, so did transmissibility, but at a slower pace than expected.

The researchers then sought to determine mobility thresholds that could keep the virus’ reproduction number below 1.0. They found that, at least in the UK, an initial 43-percent mobility reduction would be necessary, but after considering other social distancing behaviours, the threshold could be as low as 18 percent. These values varied largely for the different countries assessed.

“We found strong evidence that the relationship between mobility and transmissibility changed over time, typically, a dampening indicating that smaller reductions in mobility can result in epidemic control likely due to other social distancing behaviours,” the researchers said.

“As many countries are re-imposing social-distancing policies, our analysis illustrates that sustainable relaxation of population-wide social-distancing measures should be undertaken very carefully and replaced with equally effective control measures, such as thorough contact-tracing,” they added.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Infectious Diseases - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
05 Feb 2021

Primary immunodeficiency disease (PIDD) and allergies are two groups of conditions related to the immune system. However, they are uniquely different in terms of symptoms and treatment.

Roshini Claire Anthony, 5 days ago

Switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) did not result in worsening renal function or bone mineral density (BMD) in Asian patients with chronic hepatitis B virus (HBV) infection, according to a small real-world prospective study.

5 days ago
The standard combination therapy against paediatric migraine—consisting of a combination of parenteral medications—appears to yield moderate pain relief, which persists up to 1 week after administration, a new study has found.
Roshini Claire Anthony, 3 days ago

Critical or severe COVID-19 disease could raise the risk of negative perinatal outcomes in pregnant women, according to an observational study from the US.