Most Read Articles
09 Dec 2016
All patients with acne are potentially at risk of scarring. Professor Goh Chee Leok addresses this issue by focussing on preventing the development of scars in his talk at the 41st Annual Meeting of the Dermatological Society of Malaysia held in Kuching, Sarawak.
01 Jun 2016
Adapalene 0.3%/benzoyl peroxide 2.5% topical gel is a safe and effective treatment option in patients with moderate and severe inflammatory non-nodulocystic acne, based on a multicentre, randomised, double-blind, parallel-group study.
06 Jun 2016

The recent Paediatrics in Practice (PIP) 2016 held recently in Selangor was a success. On top of the launch of a locally published atlas, the conference also featured the introduction of DEBRA (Dystrophic Epidermolysis Bullosa Research Association), various presentations, a workshop and panel discussion on paediatric skin diseases by prominent specialists such as Dr. Tang Jyh Jong, Dr. Tan Wooi Chiang, Dr. Chan Lee Chin, Dr. Sabeera Begum and Dr. Leong Kin Fon. MIMS Doctor spoke to Dr. Thiyagar Nadarajaw, paediatrician and adolescent medicine specialist and Leong, a consultant paediatric dermatologist at the Kuala Lumpur Hospital about the PIP workshop and their thoughts on the atlas.

26 May 2016
Melasma is a benign pigmentary skin disorder. However, it features prominently on sun-exposed areas, typically the face and arms, and as such affects the quality of life of those with the disorder. Radha Chitale spoke with Dr. Gavin Ong Chun Wei, a dermatologist at The Skin Specialist clinic in Singapore, about how GPs can best diagnose and treat patients with melasma.

MKTP delivers long-term repigmentation in vitiligo, other leukodermas

30 Jul 2017

Melanocyte-keratinocyte transplantation procedure (MKTP) confers satisfactory long-term repigmentation in patients with leukoderma, with repigmentation lasting for at least 72 months, reports a recent study.

Researchers conducted a retrospective review of electronic medical records for all MKTPs performed at Henry Ford Hospital between January 2009 and April 2014 to assess long-term repigmentation of MKTP in vitiligo and other leukodermas. A 5-point grading scale (poor to excellent) and Vitiligo Area Scoring Index (VASI) were utilized to evaluate repigmentation.

MKTP was performed at 236 anatomically based lesions (ABLs) in a total of 100 patients, of which 63 with 157 ABLs had available long-term data (12 to 72 months; median 24 months).

VASI scores improved in segmental vitiligo (‒75.6±24.6 percent), nonsegmental vitiligo (‒59.2±36.6 percent) and physical leukoderma (‒32.4±33.5 percent). In vitiligo, 53 percent of ABLs maintained >75 percent repigmentation at 24 months after MKTP, 64 percent at 48 months and 53 percent at 72 months.

Age, skin photoype and anatomic location of ABLs did not show any significant impact on the outcome of treatment.

These results support a previous study, which found MKTP to be effective and well-tolerated based upon categorical and VASI assessments of repigmentation. [J Am Acad Dermatol 2012;66:785-93]

The current study is limited by the retrospective design with uncontrolled, postoperative adjuvant treatments and inconsistent compliance to scheduled follow-up evaluations, according to researchers, adding that persistence of pigmentation after MKTP is a critical consideration for efficacy.

Editor's Recommendations
Most Read Articles
09 Dec 2016
All patients with acne are potentially at risk of scarring. Professor Goh Chee Leok addresses this issue by focussing on preventing the development of scars in his talk at the 41st Annual Meeting of the Dermatological Society of Malaysia held in Kuching, Sarawak.
01 Jun 2016
Adapalene 0.3%/benzoyl peroxide 2.5% topical gel is a safe and effective treatment option in patients with moderate and severe inflammatory non-nodulocystic acne, based on a multicentre, randomised, double-blind, parallel-group study.
06 Jun 2016

The recent Paediatrics in Practice (PIP) 2016 held recently in Selangor was a success. On top of the launch of a locally published atlas, the conference also featured the introduction of DEBRA (Dystrophic Epidermolysis Bullosa Research Association), various presentations, a workshop and panel discussion on paediatric skin diseases by prominent specialists such as Dr. Tang Jyh Jong, Dr. Tan Wooi Chiang, Dr. Chan Lee Chin, Dr. Sabeera Begum and Dr. Leong Kin Fon. MIMS Doctor spoke to Dr. Thiyagar Nadarajaw, paediatrician and adolescent medicine specialist and Leong, a consultant paediatric dermatologist at the Kuala Lumpur Hospital about the PIP workshop and their thoughts on the atlas.

26 May 2016
Melasma is a benign pigmentary skin disorder. However, it features prominently on sun-exposed areas, typically the face and arms, and as such affects the quality of life of those with the disorder. Radha Chitale spoke with Dr. Gavin Ong Chun Wei, a dermatologist at The Skin Specialist clinic in Singapore, about how GPs can best diagnose and treat patients with melasma.