Most Read Articles
Roshini Claire Anthony, 29 May 2020

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

4 days ago
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Dr. Wong Soon Tee, 28 May 2020
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.
27 May 2020
The perception that proton pump inhibitors (PPIs) cause multiple serious adverse effects (AEs) is supported by many internists, who then recommend treatment cessation even in patients at high risk for upper gastrointestinal bleeding (UGIB), reveals a study.

Mindfulness-based interventions ease inflammation in IBD

22 Apr 2020
Crohn’s is not the end of the world, as Kathleen Baker’s silver medal proves

Mindfulness-based therapies appear to be effective in improving levels of inflammatory biomarkers in patients with inflammatory bowel disease (IBD), a recent study has shown.

The study included IBD patients who were randomly assigned to receive mindfulness-based interventions (n=37; mean age, 46.2±10.9 years; 29 females) or standard medical therapy (n=20; mean age, 46.3±11.9 years; 9 females). The intervention involved four internet-based modules and four face-to-face sessions. The primary outcome was the faecal calprotectin concentration.

At baseline, faecal calprotectin levels were comparable between the active intervention and standard therapy groups (198±394 vs 222±242 µg/g). After 6 months of follow-up, concentrations dropped to 128±226 µg/g in the mindfulness-based intervention group and rose to 495±949 µg/ in the standard therapy group. The resulting difference was statistically significant (–367 µg/g, 95 percent confidence interval [CI], –705 to –29; p=0.03).

Levels of C-reactive protein also changed significantly over 6 months. In the mindfulness intervention arm, concentrations jumped from 1.93±2.47 to 2.43±3.05 mg/dL. Those in the standard therapy arm experienced a similar increase but to an almost significantly greater degree (2.46±3.81 to 5.25±7.73 mg/dL; difference, –2.82; 95 percent CI, –5.70 to 0.08; p=0.05).

Changes in cortisol concentrations in the hair remained comparable between treatment arms.

“[F]uture work should be designed to try to verify these findings by evaluating several physiological indices and to increase our knowledge of the biological systems which benefit from mindfulness-based intervention-mediated reductions in stress which can therefore serve as useful biological indicators in these patients,” said researchers.

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Most Read Articles
Roshini Claire Anthony, 29 May 2020

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

4 days ago
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Dr. Wong Soon Tee, 28 May 2020
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.
27 May 2020
The perception that proton pump inhibitors (PPIs) cause multiple serious adverse effects (AEs) is supported by many internists, who then recommend treatment cessation even in patients at high risk for upper gastrointestinal bleeding (UGIB), reveals a study.