Most Read Articles
Rachel Soon, 16 Aug 2019

On 8 August, the first town hall held by the Ministry of Health (MOH) with members of the pharmacy profession took place in Putrajaya. Over 500 pharmacists from across the country and from different areas of practice—community and hospital, public and private, academy and industry—converged to fill the auditorium for the chance to engage in direct dialogue with MOH.

3 days ago
Cardiac biomarkers are useful for identifying community-acquired pneumonia (CAP) patients with an elevated risk of early and long-term cardiovascular (CV) events, according to a study.
Yesterday
Tofogliflozin is safe and effective for elderly patients with type 2 diabetes mellitus (T2DM), regardless of insulin and oral antidiabetic drugs, reports a new Japan study.
6 days ago
Pulmonary function has potential predictive value for future increases in arterial stiffness and its progression, as reported in a recent study.

Men with depression, low fertility-related QOL more likely to have erectile dysfunction

03 Aug 2019

Lower fertility-related quality of life (QOL) and depression show a robust association with erectile dysfunction in men of couples with unexplained infertility, but neither of these is associated with spermatogenesis or testosterone levels, according to a study.

This secondary analysis of a large, multicentre, randomized controlled trial in couples with unexplained fertility included 708 men (mean age, 34.2 years), who underwent baseline semen analysis with measurement of fasting total testosterone and gonadotropin. Participants also completed surveys, including the Fertility Quality of Life (FertiQOL), the Patient Health Questionnaire-9 (PHQ-9) and the International Index of Erectile Function (IIEF).

Total testosterone, with low total testosterone defined as <264 ng/dl, semen parameters and the IIEF score were the primary outcomes. Multivariable logistic regression analyses were performed, adjusting for age, race, body mass index, education, smoking, alcohol use, infertility duration and comorbidity.

Fifty-nine men (8.3 percent) had a PHQ-9 score of 5, which was consistent with depression, while 99 (14.0 percent) had low total cholesterol, and 63 (9.0 percent) had mild or worse erectile dysfunction.

The FertiQOL score and depression did not show any association with total cholesterol or any semen parameter, but the FertiQOL score inversely correlated with erectile dysfunction (for every 5-point score decline; adjusted odds ratio [aOR], 1.30, 95 percent CI, 1.16–1.46).

Furthermore, erectile dysfunction was significantly more likely to manifest in men with vs without depression (aOR, 6.31, 3.12–12.77).

“Erectile dysfunction in infertile men merits longitudinal investigation in future studies,” the investigators said.

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Most Read Articles
Rachel Soon, 16 Aug 2019

On 8 August, the first town hall held by the Ministry of Health (MOH) with members of the pharmacy profession took place in Putrajaya. Over 500 pharmacists from across the country and from different areas of practice—community and hospital, public and private, academy and industry—converged to fill the auditorium for the chance to engage in direct dialogue with MOH.

3 days ago
Cardiac biomarkers are useful for identifying community-acquired pneumonia (CAP) patients with an elevated risk of early and long-term cardiovascular (CV) events, according to a study.
Yesterday
Tofogliflozin is safe and effective for elderly patients with type 2 diabetes mellitus (T2DM), regardless of insulin and oral antidiabetic drugs, reports a new Japan study.
6 days ago
Pulmonary function has potential predictive value for future increases in arterial stiffness and its progression, as reported in a recent study.