Most Read Articles
Pearl Toh, 31 Dec 2019
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At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
5 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.
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Prevention of glucocorticoid-induced osteoporosis (GIOP) and postmenopausal osteoporosis (PMOP) remains inadequate in patients with rheumatoid arthritis (RA), as shown in a study that evaluated the implementation of the 2003 and 2014 French guidelines on the prevention and treatment of GIOP and the 2012 update of the French guidelines for the treatment of PMOP.

Men with depression, low fertility-related QOL more likely to have erectile dysfunction

03 Aug 2019

Lower fertility-related quality of life (QOL) and depression show a robust association with erectile dysfunction in men of couples with unexplained infertility, but neither of these is associated with spermatogenesis or testosterone levels, according to a study.

This secondary analysis of a large, multicentre, randomized controlled trial in couples with unexplained fertility included 708 men (mean age, 34.2 years), who underwent baseline semen analysis with measurement of fasting total testosterone and gonadotropin. Participants also completed surveys, including the Fertility Quality of Life (FertiQOL), the Patient Health Questionnaire-9 (PHQ-9) and the International Index of Erectile Function (IIEF).

Total testosterone, with low total testosterone defined as <264 ng/dl, semen parameters and the IIEF score were the primary outcomes. Multivariable logistic regression analyses were performed, adjusting for age, race, body mass index, education, smoking, alcohol use, infertility duration and comorbidity.

Fifty-nine men (8.3 percent) had a PHQ-9 score of 5, which was consistent with depression, while 99 (14.0 percent) had low total cholesterol, and 63 (9.0 percent) had mild or worse erectile dysfunction.

The FertiQOL score and depression did not show any association with total cholesterol or any semen parameter, but the FertiQOL score inversely correlated with erectile dysfunction (for every 5-point score decline; adjusted odds ratio [aOR], 1.30, 95 percent CI, 1.16–1.46).

Furthermore, erectile dysfunction was significantly more likely to manifest in men with vs without depression (aOR, 6.31, 3.12–12.77).

“Erectile dysfunction in infertile men merits longitudinal investigation in future studies,” the investigators said.

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Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
5 days ago
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.
6 days ago
Prevention of glucocorticoid-induced osteoporosis (GIOP) and postmenopausal osteoporosis (PMOP) remains inadequate in patients with rheumatoid arthritis (RA), as shown in a study that evaluated the implementation of the 2003 and 2014 French guidelines on the prevention and treatment of GIOP and the 2012 update of the French guidelines for the treatment of PMOP.