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Pank Jit Sin, 19 Nov 2018
Primary care practitioners will now have access to an expert derived handbook as reference for the treatment of urticaria. 

Men, women show different wrinkling patterns

27 Apr 2017

Lifestyle and physiological factors determine the wrinkling patterns between men and women, a recent study suggests. Less wrinkling is associated with sunburn tendency in men and with female pattern hair loss in women, whereas increased wrinkling is linked to age and current smoking in both genders.

Researchers looked at a cohort of 3,831 north-western Europeans aged 51 to 98 years (58 percent female) to investigate sex-specific determinants for facial wrinkles. Wrinkle area was quantified digitally with the use of facial photographs.

Analysis was performed using multivariable linear regression, and effect estimates were presented as the percentage difference in the mean value of wrinkle area per unit increase of a determinant (percent Δ).

Compared with women, men was found to have a greater wrinkle area (median, 4.5 percent; interquartile range [IQR], 2.9 to 6.3; vs 3.6 percent; IQR, 2.2 to 5.6). The strongest determinant of wrinkling was age. Current smoking (15.5 percent Δ for men; 30.9 percent Δ for women) and lower body mass index (1.7 percent Δ for men; 1.8 percent Δ for women) had a statistically significant association with increased wrinkling. On the other hand, pale skin colour showed a protective effect (–21.0 percent Δ for men; –28.5 percent Δ for women).

Specifically, men with sunburn tendency were likely to show less wrinkling. In women, female pattern hair loss and a higher free androgen index were associated with less wrinkling, whereas low educational levels and alcohol use were associated with increased wrinkling.

Wrinkles are among the clinical manifestation of an ageing skin, which is defined as changes in the skin occurring as a result of passage of time (chronological) or of chronic exposure to sunlight (photoageing). Skin ageing may be prevented or delayed by applying sunscreens and antioxidants, while skin wrinkles can be treated using dermal fillers. [Evid Based Complement Alternat Med 2013;doi:10.1155/2013/827248; J Cosmet Laser Ther 2016;18:301–310]

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