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01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Jairia Dela Cruz, 3 days ago
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Mediterranean diet adherence reduces colorectal cancer incidence

11 Jun 2020
The Mediterranean diet: Studies point to an increasing number of health benefits

Adherence to a Mediterranean diet is inversely associated with incidence of colorectal cancer (CRC), but not with overall mortality or CRC-specific mortality among those diagnosed with the disease, according to the results of a meta-analysis.

“Mounting epidemiologic studies have investigated the potential inverse association between Mediterranean diet adherence and CRC incidence and mortality,” the investigators said.

The investigators sought to assess the association of Mediterranean diet adherence with CRC incidence and mortality in this study. They searched the databases of PubMed, Embase, and Web of Science to identify eligible studies up to September 2019. Summary risk ratios (RRs) and 95 percent confidence intervals (CIs) were estimated using a random-effects model.

Thirteen studies met the eligibility criteria, of which nine reported CRC incidence and five CRC mortality. The summary RR of CRC incidence was 0.90 (95 percent CI, 0.84–0.96) for the highest vs lowest Mediterranean diet adherence and 0.96 (95 percent CI, 0.94–0.99) per 2-score increase in Mediterranean diet adherence.

In terms of specific cancers, the summary RRs for the highest vs lowest Mediterranean adherence were 0.82 (95 percent CI, 0.71–0.95) for rectal cancer, 0.94 (95 percent CI, 0.87–1.02) for proximal colon cancer, and 0.91 (95 percent CI, 0.79–1.04) for distal colon cancer.

Statistical significance was not achieved in neither the summary HR of overall mortality for the highest vs lowest pre- and postdiagnosis Mediterranean diet adherence nor the summary HR of CRC-specific mortality for the highest vs lowest prediagnosis Mediterranean diet adherence.

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Most Read Articles
01 Dec 2020
Tetanus toxoid 5 Lf, diphtheria toxoid 2 Lf, pertussis toxoid 2.5 mcg, filamentous haemagglutinin 5 mcg, fimbriae types 2 and 3 5 mcg, pertactin 3 mcg
Dr. Hsu Li Yang, Dr. Tan Thuan Tong, Dr. Andrea Kwa, 08 Jan 2021
Antimicrobial resistance has become increasingly dire as the rapid emergence of drug resistance, especially gram-negative pathogens, has outpaced the development of new antibiotics. At a recent virtual symposium, Dr Hsu Li Yang, Vice Dean (Global Health) and Programme Leader (Infectious Diseases), NUS Saw Swee Hock School of Public Health, presented epidemiological data on multidrug-resistant (MDR) gram-negative bacteria (GNB) in Asia, while Dr Tan Thuan Tong, Head and Senior Consultant, Department of Infectious Diseases, Singapore General Hospital (SGH), focused on the role of ceftazidime-avibactam in MDR GNB infections. Dr Andrea Kwa, Assistant Director of Research, Department of Pharmacy, SGH, joined the panel in an interactive fireside chat, to discuss challenges, practical considerations, and solutions in MDR gram-negative infections. This Pfizer-sponsored symposium was chaired by Dr Ng Shin Yi, Head and Senior Consultant of Surgical Intensive Care, SGH.
Jairia Dela Cruz, 3 days ago
Spending too much time sitting cannot be good for the body, and rising to one's feet breaks up such a behaviour and yields small, but meaningful, reductions in certain cardiovascular disease (CVD) risk factors, according to the results of a meta-analysis.
3 days ago
Use of thyroid hormone therapy does not seem to protect older adults with subclinical hypothyroidism against mortality, but it appears to confer survival benefits to those aged <65 years, results of a study have shown.