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Maternal refined-grain intake ups risk of overweight, obesity in offspring

19 Jul 2017
It was found that those who consumed a higher intake of whole grains were at a lower risk of heart problems.

Mothers who have high consumption of refined grains during pregnancy are likely to have offspring with higher body mass index z score (BMIZ) and greater risk of overweight or obesity at age 7 years, a recent study has found.

Researchers performed a prospective analysis of refined-grain intake during pregnancy in association with offspring growth through age 7 years among high-risk children born to women with gestational diabetes mellitus (GDM). A total of 918 mother‒singleton child dyads from the Danish National Birth Cohort were included.

Offspring BMIZs were estimated using weight and length or height measured at birth, 5 and 12 months, and 7 years. Researchers used linear and Poisson regressions, adjusting for maternal demographic, lifestyle and dietary factors.

Maternal refined-grain intake during pregnancy positively correlated with offspring BMIZ (adjusted β per serving increase per day, 0.09; 95 percent CI, 0.02 to 0.15) and risk of overweight or obesity at age 7 years (adjusted risk ratio [aRR] comparing the highest with the lowest quartile, 1.80; 1.09 to 2.98; p=0.032 for trend). This association was more evident among children who were breastfed <6 months.

Replacing one serving of refined grains per day with an equal serving of whole grains during pregnancy was associated with a 10-percent reduction in risk of offspring overweight or obesity at age 7 years (aRR, 0.90; 0.82 to 0.98). There were no associations between refined-grain intake and infant growth.

“The findings highlight pregnancy as a potential window of susceptibility associated with offspring growth and obesity risk among this high-risk population,” researchers said. “Data with longer follow-up are warranted.”

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Most Read Articles
09 Apr 2016
Among adolescents who have only received diphtheria, tetanus toxoids, acellular pertussis (DTaP) vaccines in childhood, tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine provides moderate protection against pertussis during the first year and then wanes rapidly thereafter.
26 Jul 2007
Despite the prevalence of corticosteroid use in infants with bronchiolitis, data on its efficacy is insufficient. In this study, oral dexamethasone was compared with placebo in the treatment of bronchiolitis.