Most Read Articles
15 Jan 2018
Body surface area (BSA) affected by psoriasis can be measured to target diabetes prevention efforts for patients with psoriasis, a recent study suggests.
Pearl Toh, 14 Apr 2018
Taking the oral extract product of the fern Polypodium leucotomos (PLE) on top of the standard topical hydroquinone cream and sunscreen reduces the severity of melasma to a greater extent compared with the standard treatment alone in Asian patients, a pilot study has shown.
Jan Welch, 01 Jun 2011

Sexually transmitted infections (STIs) are common, with rates of many infections increas­ing over the last two decades.1 Community screening studies in the UK have shown a prevalence of about 10% for chlamydial infection2 and (among women screened in an urban setting) 3% for gonorrhoea.3 In women (Figure 1), these potentially serious infections are often asymptomatic, whereas the presence of symptoms such as vaginal discharge generally indicates a less pathogenic (but still potentially debilitating) infection, with an organism such as Candida. STIs are often multiple, and the finding of one infection should prompt consider­ation of testing for others. Many sexual health services now initially provide screening tests for asymptomatic women, but a more comprehensive assessment—comprising detailed history4 and genital examination5—is usually necessary when symptoms are present.

Stephen Padilla, 4 days ago
High use of hydrochlorothiazide (HCTZ) appears to significantly increase the risk of nonmelanoma skin cancer (NMSC), particularly squamous cell carcinoma (SCC), suggests a recent study. Use of other diuretic and antihypertensive medications does not appear to be linked to NMSC.

Malnutrition leads to worse quality of life in systemic sclerosis patients

07 Apr 2018

Severe malnutrition appears to negatively affect quality of life (QoL) in patients with systemic sclerosis, which underscores the importance of routine and standardized nutritional screenings as well as appropriate and multimodal interventions, a recent study has shown.

Using the Malnutrition Universal Screening Tool (MUST), researchers assessed the nutritional status of 129 systemic sclerosis patients (mean age 59.1±13.8 years; 90.7 percent female). The Short Form 36 Questionnaire (SF-36) and the Scleroderma Health Assessment Questionnaire (SHAQ) were used to evaluate participant QoL.

According to the MUST results, 14.7 percent (n=19) of patients were at medium risk of malnutrition while 10.9 percent (n=14) were at high risk. There were 14 malnourished participants, in whom the mean body mass index was significantly lower (p<0.001) and weight loss was significantly more common (p<0.001).

Almost all measures of quality of life in the SF-36 was significantly worse in malnourished participants. For instance, the mean scores in the physical functioning (15.0 vs 60.0; p<0.001), general health (32.0 vs 45.0; p=0.008), vitality (31.3 vs 50.0; p<0.001) and social functioning (37.5 vs 75.0; p<0.001) were all significantly higher in well-nourished participants.

Similarly, findings for the mental health (55 vs 70.0; p=0.028), role physical (18.8 vs 50.0; p<0.001) and role emotional (25 vs 66.7; p=0.005) domains were significantly worse in malnourished participants. Only SF-36-defined bodily pain was comparable between the two patient groups (31.0 vs 41.0; p=0.124).

By comparison, the SHAQ score, which measures disease-specific QoL, was significantly higher in the malnourished participants, indicating greater disease-specific impairments (1.7 vs 0.9; p<0.001).

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Most Read Articles
15 Jan 2018
Body surface area (BSA) affected by psoriasis can be measured to target diabetes prevention efforts for patients with psoriasis, a recent study suggests.
Pearl Toh, 14 Apr 2018
Taking the oral extract product of the fern Polypodium leucotomos (PLE) on top of the standard topical hydroquinone cream and sunscreen reduces the severity of melasma to a greater extent compared with the standard treatment alone in Asian patients, a pilot study has shown.
Jan Welch, 01 Jun 2011

Sexually transmitted infections (STIs) are common, with rates of many infections increas­ing over the last two decades.1 Community screening studies in the UK have shown a prevalence of about 10% for chlamydial infection2 and (among women screened in an urban setting) 3% for gonorrhoea.3 In women (Figure 1), these potentially serious infections are often asymptomatic, whereas the presence of symptoms such as vaginal discharge generally indicates a less pathogenic (but still potentially debilitating) infection, with an organism such as Candida. STIs are often multiple, and the finding of one infection should prompt consider­ation of testing for others. Many sexual health services now initially provide screening tests for asymptomatic women, but a more comprehensive assessment—comprising detailed history4 and genital examination5—is usually necessary when symptoms are present.

Stephen Padilla, 4 days ago
High use of hydrochlorothiazide (HCTZ) appears to significantly increase the risk of nonmelanoma skin cancer (NMSC), particularly squamous cell carcinoma (SCC), suggests a recent study. Use of other diuretic and antihypertensive medications does not appear to be linked to NMSC.