Most Read Articles
Pearl Toh, 20 Nov 2019
The trade-off between the risk of ischaemic vs bleeding events may be different between Asian and non-Asian patients, which warrants careful consideration when deciding on the duration of antiplatelet therapy following a percutaneous coronary intervention (PCI), according to a presentation at ESC Asia Congress 2019.
4 days ago
Participating in a long-distance skiing event may help lower the risk of hypertension, with the number of completed races showing a weak association with the risk, a study has found.
06 Sep 2019
Hypertensive adults with lower plasma zinc concentration are at increased risk of haemorrhagic stroke, especially those with higher body mass index or lower plasma copper levels, a study has found.
06 Jan 2020
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.

Lower SBP tied to reduced risk of CVD in older patients

01 Nov 2019
The impacts of loosened blood pressure guidelines

Blood pressure (BP) that is lower than currently recommended levels does not pose any harm in older patients without previous cardiovascular disease (CVD), according to a study. The association between lower systolic (S)BP and lesser risk of CVD suggests the benefit of having a lower SBP.

Of the 31,704 patients included, 26,663 were aged 40–75 years and 5,041 were 76–90 years. Mean follow-up was 2 years. There were no significant differences in risk of any outcome among younger patients, but an association was found between low BP and the lowest risk of CVD in the older group.

The incidence of CVD was lower in older patients in the 110–129 mm Hg group when compared with the reference group. After adjustment for covariates, older patients in this group had a hazard ratio (HR) for CVD of 0.60 (95 percent CI, 0.40–0.92) as compared with the reference group.

This study sought to compare the risk of CVD—nonfatal acute myocardial infarction (AMI) or stroke—at BP levels that met current recommendations with risk at lower levels, especially in older patients. The authors identified individuals with hypertension aged 40–90 years from a primary care register. Those with a history of cancer, diabetes mellitus or CVD were not included.

Patients were divided into age groups of 40–75 years and 76–90 years and into SBP groups of 110–129, 130–139 (reference), 140–149 and ≥150 mm Hg. The Kaplan-Meier estimator was used to examine the incidence of AMI, stroke and a composite of the two. HRs for outcomes were estimated using Cox proportional hazards regression.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Cardiology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 20 Nov 2019
The trade-off between the risk of ischaemic vs bleeding events may be different between Asian and non-Asian patients, which warrants careful consideration when deciding on the duration of antiplatelet therapy following a percutaneous coronary intervention (PCI), according to a presentation at ESC Asia Congress 2019.
4 days ago
Participating in a long-distance skiing event may help lower the risk of hypertension, with the number of completed races showing a weak association with the risk, a study has found.
06 Sep 2019
Hypertensive adults with lower plasma zinc concentration are at increased risk of haemorrhagic stroke, especially those with higher body mass index or lower plasma copper levels, a study has found.
06 Jan 2020
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.