Most Read Articles
07 Aug 2016
Pravastatin supplementation is associated with improved pregnancy outcomes among women with refractory obstetric antiphospholipid syndrome (APS) who developed preeclampsia (PE) or intrauterine growth restriction (IUGR) during standard antithrombotic therapy, according to a study.
Roshini Claire Anthony, 07 Sep 2016

Estrogen receptor α (ESR1) mutations Y537S and D538G are associated with reduced overall survival (OS) in patients with human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer, according to findings of a secondary analysis of the BOLERO-2* clinical trial.

Christina Leung, Robert Chin, 19 Sep 2017
This review article outlines the prevalence of nausea and vomiting of pregnancy (NVP) and hyperemesis gravidarum (HG), definition of NVP and HG, aetiology, risk factors, complications of HG, recommended investigations, primary care management, hospital and ambulatory daycare, therapeutic management of HG supported by good clinical evidence, discharge planning, and importance of the multidisciplinary team to provide high quality care in patients with NVP and HG.

Lower limb muscle best predictor of functional capacity in active postmenopausal women

18 Sep 2017

Functional capacity (FC) in active postmenopausal women depends more on lower limb muscle strength than on abdominal obesity, suggesting that those with abdominal obesity may not necessarily have a reduced FC as long as lower limb muscle strength is preserved, according to a study.

The study included 44 active women (>7,500 steps/day) aged between 50 and 70 years. Assessments included body composition and distribution (dual-energy X-ray absorptiometry), FC (chair-stand, alternate-step and one-leg-stance tests), handgrip strength and knee extensor strength (dynamometry), steps/day (accelerometer) and cardiorespiratory function (spirometry/VO2max).

Results showed no correlation between body composition or body mass index and FC score. However, FC score significantly correlated with waist circumference (p=0.024), handgrip (p=0.036), knee extensor strength (p=0.003) and VO2max (p=0.006).

Additionally, when the highest FC quartile was compared with the lowest one, a significant difference in knee extensor strength (p=0.003) was observed. Knee extensor strength was also the only variable inserted into the FC prediction equation derived from the stepwise regression model (p=0.003).

The correlation observed between waist circumference and FC among active postmenopausal women confirms that an association exists between abdominal obesity and FC even in older women practicing physical activity daily, researchers said.

“However, it contradicts [previous reports] demonstrating that waist circumference is a reliable index to predict functional capacities, because our study did not demonstrate that waist circumference has a predictive capacity with regard to physical function in nonsedentary older women,” they added.

Researchers pointed out that waist circumference was not significantly associated with the chair-stand test and the alternate-step test score, but rather only with the one-leg stance test. This implies that abdominal fat accumulation might affect the centre of gravity and, therefore, balance to a greater extent than muscle strength and power required to stand from a chair or to climb stairs.

“It can be argued that women practicing physical activity spontaneously do more functional exercises that simulate activities of daily living than specific training aimed at improving balance,” researchers continued.

More studies with a larger battery of tests to determine FC, as well as mobility, are needed to confirm the present data, they said.

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Most Read Articles
07 Aug 2016
Pravastatin supplementation is associated with improved pregnancy outcomes among women with refractory obstetric antiphospholipid syndrome (APS) who developed preeclampsia (PE) or intrauterine growth restriction (IUGR) during standard antithrombotic therapy, according to a study.
Roshini Claire Anthony, 07 Sep 2016

Estrogen receptor α (ESR1) mutations Y537S and D538G are associated with reduced overall survival (OS) in patients with human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer, according to findings of a secondary analysis of the BOLERO-2* clinical trial.

Christina Leung, Robert Chin, 19 Sep 2017
This review article outlines the prevalence of nausea and vomiting of pregnancy (NVP) and hyperemesis gravidarum (HG), definition of NVP and HG, aetiology, risk factors, complications of HG, recommended investigations, primary care management, hospital and ambulatory daycare, therapeutic management of HG supported by good clinical evidence, discharge planning, and importance of the multidisciplinary team to provide high quality care in patients with NVP and HG.