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Lower BMI, hand grip strength seen in advanced COPD patients

13 Sep 2020

A recent study has shown notable characteristics of patients with chronic obstructive pulmonary disease (COPD) in advanced stages, which include decreased body mass index (BMI), fat-free body mass, hand grip strength, and respiratory and skeletal muscle functions.

The investigators sought to evaluate the nutritional statuses of COPD patients in four categories of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2015 classification and to examine the associations of BMI and fat-free mass index with respiratory and skeletal muscle strengths.

A total of 463 COPD patients aged ≥40 years who were followed for at least a year were included in this prospective observational study. Medical histories, smoking status, and anthropometric, spirometry, and hand grip strength measurements were recorded.

Participants were classified according to GOLD as follows: group A (n=119), group B (n=58), group C (n=117), and group D (n=169). Patients in group D were older than those in other groups (p=0.001). No between-group difference was found in terms of sex (p=0.163).

Fat-free body mass was significantly lower in group D than in group A (p=0.014), and BMI was decreased in groups C and D compared with other groups (p=0.001). Furthermore, a significant decreasing trend in spirometry and hand grip strength was observed in group D patients (p<0.001 for both).

“Nutritional status should be routinely monitored and considered an important indicator in COPD,” the investigators said.

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Most Read Articles
22 Nov 2020
Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

4 days ago
Vitamin D deficiency may be a contributing factor to the mortality rate among patients with the novel coronavirus disease (COVID-19), reports a new study.
Pearl Toh, 3 days ago
Inhaled corticosteroid (ICS) should be the mainstay of long-term asthma management — such is the key message of the latest Singapore ACE* Clinical Guidance (ACG) for asthma, released in October 2020.