Most Read Articles
Roshini Claire Anthony, 12 Nov 2018

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
14 Nov 2018
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
3 days ago
Higher exposure to ticagrelor following myocardial infarction does not appear to contribute to an increased risk of intracranial haemorrhage, which is associated with age and prior cardiovascular morbidities, according to a study.

Low vitamin D levels may be detrimental to respiratory health

13 Feb 2018

Decreased serum vitamin D levels appear to confer an increased risk of asthma, bronchitis, wheeze and chest tightness, a study reports. Conversely, increased vitamin D levels are associated with higher levels of lung function.

Researchers examined 5,011 adults (mean age 58 years; 45 percent male), analysing data on serum 25-hydroxyvitamin D (25OHD) and history of respiratory disease. All participants underwent spirometry and completed a questionnaire detailing respiratory symptoms.

Analysis was performed using logistic and linear regression models with adjustments for age, sex, season and smoking (model A), plus body mass index and physical activity level (model B), plus history of chronic diseases (model C).

Of the patients, 10 percent were current smokers and 12 percent were taking vitamin D supplements. The prevalence rate of vitamin D deficiency (25OHD level <50 nmol/L) was 8.0 percent.

All three models showed that participants with 25OHD <50 nmol/L had higher odds of having asthma (model C: odds ratio [OR], 1.32; 95 percent CI, 1.00–1.73), bronchitis (OR, 1.54; 1.17–2.01), wheeze (OR, 1.37; 1.10–1.71) and chest tightness (OR, 1.42; 1.10–1.83).

On the other hand, participants with vitamin D level >100 nmol/L had greater forced vital capacity compared with those who had vitamin D level 50–100 nmol/L group in all the three models (model C: coefficient, 1.17; 0.18–2.15).

The findings indicate that respiratory illness and symptoms are related to lower vitamin D levels, researchers said.

Taken together with evidence from recent studies investigating asthma outcomes and use of vitamin D supplements, the data strengthen the proposed mechanistic relationship between vitamin D deficiency and respiratory disease, they added. [J Allergy Clin Immunol 2017;139:1508-1517; Cochrane Database Syst Rev 2016;9:CD011511]

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Most Read Articles
Roshini Claire Anthony, 12 Nov 2018

Patients with mild hypertension who are at low risk for cardiovascular disease (CVD) do not appear to derive mortality or CVD benefit from antihypertensive treatments, raising questions on the need for treatment in this population, according to a recent study from England.

Pearl Toh, 09 Nov 2018
A personalized computerized neurofeedback intervention for training attention and memory shows potential in cognitive training for healthy elderly men, who improved in cognitive performance after the training, although no significant improvements were seen in the overall study population.
14 Nov 2018
Type 1 diabetes impairs cognitive functioning in children, and this effect is exacerbated by extreme glycaemic levels, according to a recent meta-analysis.
3 days ago
Higher exposure to ticagrelor following myocardial infarction does not appear to contribute to an increased risk of intracranial haemorrhage, which is associated with age and prior cardiovascular morbidities, according to a study.