Most Read Articles
Yesterday
Exposure to corticosteroids in patients with autoimmune hepatitis (AIH) appears to contribute to increased risks of cataract, diabetes and bone fractures, a study has found. Notably, the fracture risk is elevated at low doses, while the risk of adverse events overall is dose-dependent and is reversible.
6 days ago
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Supplementation with omega-3 fatty acids or vitamin D3 for up to 5 years has no effect on kidney function in adults with type 2 diabetes (T2D), the VITAL-DKD* ancillary study has shown.
Jairia Dela Cruz, 4 days ago
Many patients with nonvalvular atrial fibrillation (NVAF) in Thailand use anticoagulants, but the uptake of nonvitamin-K oral anticoagulants remains suboptimal despite showing an upward trend, according to data from the COOL-AF registry presented at the European Society of Cardioloy (ESC) Asia Congress 2019 with APSC and AFC.

Low income, obesity may worsen quality of life in patients with nephrolithiasis

05 Jul 2019

Quality of life (QoL) tends to be lower among patients with kidney stones who are morbidly obese, unemployed or have low income, a recent study has shown.

“While clinical characteristics such as body mass and stone disease severity were also associated with health-related QoL, this study shows that socioeconomic factors are similarly important,” the investigators said.

In total, 2,057 stone formers completed the Wisconsin Stone Quality of Life (WISQOL) questionnaire. Lower income (β, 0.372; p=0.014), body mass index >40 kg/m2 (β, –0.380; p<0.001) and unemployed status (β, –0.291; p=0.008) were found to be independently associated with worse health-related QoL.

Apart from these factors, the following also correlated independently with significantly lower health-related QoL: female gender (β, –0.204; p<0.001), nonwhite race (β, –0.299; p=0.001), five or more medical comorbidities (β, –0.354; p=0.001), severe recurrent stone formation (β, –0.146; p=0.045), enrolment at an acute care visit or a preoperative or postoperative appointment (β, –0.548; p<0.001), and recent symptoms (β, –0.892; p<0.001).

“Further research to understand the specific mechanisms by which socioeconomic status and race impact health may lend insight into methods to optimize clinical treatment of stone formers and patients with other chronic diseases,” the investigators said.

This study administered the WISQOL to patients with stones at a total of 11 stone centres across the United States. Patient ZIP Code was used to estimate household income. A mixed effects regression model was generated for analysis, with ZIP Code as the random intercept.

“Kidney stones are a source of significant morbidity which have been shown to negatively impact health-related QoL,” the investigators noted.

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Most Read Articles
Yesterday
Exposure to corticosteroids in patients with autoimmune hepatitis (AIH) appears to contribute to increased risks of cataract, diabetes and bone fractures, a study has found. Notably, the fracture risk is elevated at low doses, while the risk of adverse events overall is dose-dependent and is reversible.
6 days ago
In patients with atrial fibrillation (AF) and stable coronary artery disease (CAD), rivaroxaban monotherapy is noninferior to combination treatment with an antiplatelet therapy in terms of cutting the risk of cardiovascular events and mortality, according to data from the AFIRE trial.
Elvira Manzano, 12 Nov 2019
Supplementation with omega-3 fatty acids or vitamin D3 for up to 5 years has no effect on kidney function in adults with type 2 diabetes (T2D), the VITAL-DKD* ancillary study has shown.
Jairia Dela Cruz, 4 days ago
Many patients with nonvalvular atrial fibrillation (NVAF) in Thailand use anticoagulants, but the uptake of nonvitamin-K oral anticoagulants remains suboptimal despite showing an upward trend, according to data from the COOL-AF registry presented at the European Society of Cardioloy (ESC) Asia Congress 2019 with APSC and AFC.