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Low income, obesity may worsen quality of life in patients with nephrolithiasis

05 Jul 2019

Quality of life (QoL) tends to be lower among patients with kidney stones who are morbidly obese, unemployed or have low income, a recent study has shown.

“While clinical characteristics such as body mass and stone disease severity were also associated with health-related QoL, this study shows that socioeconomic factors are similarly important,” the investigators said.

In total, 2,057 stone formers completed the Wisconsin Stone Quality of Life (WISQOL) questionnaire. Lower income (β, 0.372; p=0.014), body mass index >40 kg/m2 (β, –0.380; p<0.001) and unemployed status (β, –0.291; p=0.008) were found to be independently associated with worse health-related QoL.

Apart from these factors, the following also correlated independently with significantly lower health-related QoL: female gender (β, –0.204; p<0.001), nonwhite race (β, –0.299; p=0.001), five or more medical comorbidities (β, –0.354; p=0.001), severe recurrent stone formation (β, –0.146; p=0.045), enrolment at an acute care visit or a preoperative or postoperative appointment (β, –0.548; p<0.001), and recent symptoms (β, –0.892; p<0.001).

“Further research to understand the specific mechanisms by which socioeconomic status and race impact health may lend insight into methods to optimize clinical treatment of stone formers and patients with other chronic diseases,” the investigators said.

This study administered the WISQOL to patients with stones at a total of 11 stone centres across the United States. Patient ZIP Code was used to estimate household income. A mixed effects regression model was generated for analysis, with ZIP Code as the random intercept.

“Kidney stones are a source of significant morbidity which have been shown to negatively impact health-related QoL,” the investigators noted.

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Most Read Articles
6 days ago
Cardiac biomarkers are useful for identifying community-acquired pneumonia (CAP) patients with an elevated risk of early and long-term cardiovascular (CV) events, according to a study.
3 days ago
Tofogliflozin is safe and effective for elderly patients with type 2 diabetes mellitus (T2DM), regardless of insulin and oral antidiabetic drugs, reports a new Japan study.
17 Aug 2019
Pulmonary function has potential predictive value for future increases in arterial stiffness and its progression, as reported in a recent study.
19 Aug 2019
Systolic blood pressure appears to have a strong association with aneurysmal subarachnoid haemorrhage (aSAH) but not with unruptured intracranial aneurysm (UIA), whereas current smoking and female sex are risk factors for both conditions, a study has found.