Most Read Articles
Elaine Soliven, 4 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 5 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 4 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.

Low-GI diets help reduce weight in prediabetic, diabetic individuals

15 Oct 2019

Diets with low glycaemic index (GI) appear to be beneficial for glycaemic control and may even reduce body weight in people with prediabetes or diabetes, according to the results of a systematic review and meta-analysis.

The investigators tried to determine whether low-GI diets were indeed superior to other diet types in lowering measures of blood glucose control in people with type 1 or type 2 diabetes or impaired glucose tolerance.

PubMed, the Cochrane Library, Embase and clinical trials registries were searched for published and unpublished studies through 1 March 2019. Fifty-four randomized controlled trials in adults or children with impaired glucose tolerance, type 1 or type 2 diabetes were included in the meta-analysis.

The investigators then synthesized continuous data using a random-effects, inverse variance models and presented these as standardized mean differences with 95 percent confidence intervals (CIs).

A low-GI diet effectively reduced glycated haemoglobin (HbA1c), fasting glucose, body mass index, total cholesterol and low-density lipoprotein. However, it did not have any effect on fasting insulin, high-density lipoprotein, triglycerides, Homeostatic Model Assessment of Insulin Resistance scores or insulin requirements.

The reduction in fasting glucose and HbA1c had an inverse relationship with body weight. Moreover, studies of the longest duration demonstrated the greatest decrease in fasting blood glucose.

“Low-GI diets are thought to reduce postprandial glycemia, resulting in more stable blood glucose concentrations,” the investigators noted.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Elaine Soliven, 4 days ago

Switching from efavirenz/emtricitabine/tenofovir disoproxil fumarate (EFV/FTC/TDF) to the new bictegravir/ emtricitabine/tenofovir alafenamide (BIC/FTC/TAF) regimen maintained high rates of virological suppression in adults who are living with HIV*, according to a study presented at AIDS 2020.

3 days ago
Among individuals with abdominal obesity, drinking beverages with artificial sweeteners (ASBs) or no sugar (USBs) instead of sugar-sweetened beverages (SSBs) helps lose body weight, a study has found. However, USBs have a more favourable effect on sweet taste preference compared with ASBs.
Stephen Padilla, 5 days ago
Pre-exposure prophylaxis (PrEP) containing either long-acting injectable cabotegravir (CAB) or tenofovir/emtricitabine (TDF/FTC) is safe and effective for transgender women (TGW) and cisgender men who have sex with men (MSM), but CAB results in a much lower HIV incidence compared to TDF/FTC, results of the HIV Prevention Trials Network (HPTN) 083 have shown.
Jairia Dela Cruz, 4 days ago
Monthly prophylaxis with the fixed-dose combination of naphthoquine-azithromycin (NQAZ) is well tolerated and confers significant protection against infection with Plasmodium parasites among individuals residing in malaria-endemic areas in Southeast Asia, as shown in the results of a phase III trial.