Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Pearl Toh, 6 days ago
Obeticholic acid significantly improves fibrosis and disease activity in patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease currently with no approved therapy, according to an interim analysis of the landmark REGENERATE* study.
12 Jan 2020
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.

Low-GI diets help reduce weight in prediabetic, diabetic individuals

15 Oct 2019

Diets with low glycaemic index (GI) appear to be beneficial for glycaemic control and may even reduce body weight in people with prediabetes or diabetes, according to the results of a systematic review and meta-analysis.

The investigators tried to determine whether low-GI diets were indeed superior to other diet types in lowering measures of blood glucose control in people with type 1 or type 2 diabetes or impaired glucose tolerance.

PubMed, the Cochrane Library, Embase and clinical trials registries were searched for published and unpublished studies through 1 March 2019. Fifty-four randomized controlled trials in adults or children with impaired glucose tolerance, type 1 or type 2 diabetes were included in the meta-analysis.

The investigators then synthesized continuous data using a random-effects, inverse variance models and presented these as standardized mean differences with 95 percent confidence intervals (CIs).

A low-GI diet effectively reduced glycated haemoglobin (HbA1c), fasting glucose, body mass index, total cholesterol and low-density lipoprotein. However, it did not have any effect on fasting insulin, high-density lipoprotein, triglycerides, Homeostatic Model Assessment of Insulin Resistance scores or insulin requirements.

The reduction in fasting glucose and HbA1c had an inverse relationship with body weight. Moreover, studies of the longest duration demonstrated the greatest decrease in fasting blood glucose.

“Low-GI diets are thought to reduce postprandial glycemia, resulting in more stable blood glucose concentrations,” the investigators noted.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Pearl Toh, 31 Dec 2019
Adding the neuraminidase inhibitor oseltamivir to usual care speeds up recovery from influenza-like illness by a day compared with usual care alone, with even greater benefits seen in older, sicker patients with comorbidities, according to the ALIC4E study.
23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
Pearl Toh, 6 days ago
Obeticholic acid significantly improves fibrosis and disease activity in patients with nonalcoholic steatohepatitis (NASH), a chronic liver disease currently with no approved therapy, according to an interim analysis of the landmark REGENERATE* study.
12 Jan 2020
Testosterone treatment may slightly improve sexual functioning and quality of life in men without underlying organic causes of hypogonadism, but it offers little to no benefit for other common symptoms of ageing, according to a study. In addition, long-term efficacy and safety of this therapy remain unknown.