Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Low-fat, high-cholesterol diet better for weight loss

10 Jul 2017
You can retrain your brain to curb sugary and fatty cravings and pick healthy choices.

In a Chinese population, consumption of low-fat, high-cholesterol diets is less likely to result in excessive weight gain and worse cardiometabolic risk profiles as compared with high-fat, low-cholesterol diets, a new randomized controlled-feeding trial shows.

The study included 307 healthy adults aged between 18 and 35 years and with body mass index (BMI) <28. Participants were then randomized to receive one of three isocaloric diets: low-fat, high-carbohydrate (n=101), moderate-fat and carbohydrate (n=105), and high-fat, low-carbohydrate (n=101).

Participants were instructed to avoid excessive exercise during the study period and were made to strictly follow one of the three prescribed diets. The primary outcome was body weight measured every month.

The mean baseline BMI for the low-fat, moderate-fat and high-fat diet groups were 21.7, 21.8 and 21.9 kg/m2. The reported rates of adherence to the diets were high (93 to 98 percent), as were the level of satisfaction (8 to 8.5).

While all dietary groups lost weight over the course of the study, the weight loss was significantly greater in the low-fat diet group vs the moderate- and high-fat diet groups (p<0.001 for interaction).

Similarly, waist circumference reductions were observed in all groups, with the low-fat diet group showing the highest reductions (p<0.0001 for interaction)

Of the 245 participants whocompleted the study, the overall changes in weight were -1.6 (95 percent CI, -1.7 to -1.4) kg for the low-fat diet group, -1.1 (-1.3 to -0.8) kg for the moderate-fat group and -1.0 (-1.3 to -0.7) for the high-fat group.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.