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Jackey Suen, 6 days ago

Prognostic nutrition index (PNI) strongly predicts clinical outcomes in patients with locally advanced non-small-cell lung cancer (NSCLC), according to two studies presented at the International Association for the Study of Lung Cancer 19th World Conference on Lung Cancer (WCLC 2018).

Low-dose morphine better than weak opioids for moderate cancer pain

17 Feb 2016
A randomized trial has shown that compared to weak opioids, low-dose morphine significantly reduced pain intensity in cancer patients with moderate pain.

The study subjects were randomized to receive either low-dose morphine (n=118) or a weak-opioid agent (n=122). A 20 percent pain intensity reduction was seen in 88.2 percent of the subjects in the morphine group and 57.7 percent in the weak-opioid group (P=0.001).

The morphine group also had a higher percentage of responders by week 1 of treatment. In addition, the same treatment group had significantly higher clinically meaningful (more than 30 percent) and highly meaningful (more than 50 percent) pain reduction.

Inadequate analgesia in the weak-opioid group resulted to frequent change in the assigned treatment.
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Most Read Articles
Jackey Suen, 6 days ago

Prognostic nutrition index (PNI) strongly predicts clinical outcomes in patients with locally advanced non-small-cell lung cancer (NSCLC), according to two studies presented at the International Association for the Study of Lung Cancer 19th World Conference on Lung Cancer (WCLC 2018).