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Roshini Claire Anthony, 5 days ago

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Pearl Toh, 29 Jun 2020
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Low-dose analgesics not a threat to male fecundity

29 Jun 2020

The use of pain medications at low doses by men does not hurt their chances of getting their partners pregnant, a study suggests.

Researchers looked at 1,956 men participating in Pregnancy Study Online. All male and female participants completed questionnaires on socio-demographics, lifestyle, medication use, and medical history at baseline. The women also accomplished bimonthly follow-up questionnaires for up to 12 months.

Of the male participants, more than half (51.7 percent) reported using at least one pain medication during the previous month. Commonly used analgesics were ibuprofen (35.8 percent) and acetaminophen (17.8 percent), with fewer men taking naproxen (5.7 percent) and aspirin (4.5 percent). The median cumulative monthly doses were 1,200, 1,300, 1,100, and 1,000 mg, respectively.

In proportional probabilities models, adjusted fecundability ratios were 1.02 (95 percent confidence interval [CI], 0.91–1.13) for ibuprofen, 0.89 (95 percent CI, 0.77–1.03) for acetaminophen, 1.07 (95 percent CI, 0.85–1.35) for naproxen, and 1.05 (95 percent CI, 0.81–1.35) for aspirin, as compared with nonuse of each medication.

Younger men (<30 years) who used some types of pain medication appeared to have reduced fecundability, although small numbers prevented the researchers from drawing a firm conclusion.

The present data, along with currently available evidence from the literature, indicate the safety of common over-the-counter pain medications at low cumulative doses in relation to male fecundity, according to the researchers.

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Most Read Articles
Roshini Claire Anthony, 5 days ago

Children who are fully vaccinated against the flu, ie, receive the recommended number of influenza vaccine doses, have a lower risk of acquiring influenza compared with those who are partially vaccinated, a US study found.

06 Jul 2020
Routinely used for treating cardiovascular diseases, statins have been shown to benefit other conditions, and new evidence suggests that using the drug at high intensity reduces the risk of hip or knee replacement, an effect that may be specific to rheumatoid arthritis.
Yesterday
Treatment with levothyroxine appears to have no significant impact on systolic and diastolic heart function in older adults with mild subclinical hypothyroidism as compared with placebo, results of a study have shown.
Pearl Toh, 29 Jun 2020
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.