Most Read Articles
Yesterday
In patients with rheumatoid arthritis (RA) who are also positive for anticitrullinated protein antibodies (ACPA), tocilizumab (TCZ) treatment for 2 years increases femoral neck bone mineral density (BMD) and decreases concentrations of bone resorption markers, a recent study has found.
3 days ago
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
5 days ago
There appears to be a paradox in the context of smoking and the risk of psoriatic arthritis (PsA), such that current smoking increases the risk of developing PsA in the general population but protects against the same risk among patients with psoriasis, according to a study.
02 Nov 2017
In this issue of MIMS Anti-Infective Supplement, we bring you clinical updates related to combating infectious diseases, and also a symposium highlight in conjunction with the launch of ceftolozane/tazobactam (Zerbaxa; Merck Sharp & Dohme Sdn Bhd) in Malaysia. 

Longer sleep tied to better metabolic profile

09 Aug 2017
Many studies have investigated various risk factors that can contribute to snoring as well as its effects.

Longer sleep duration is positively associated with better metabolic profiles, a new study has shown. On the other hand, there is no direct correlation between sleep duration and dietary intake.

Analysis of sleep data of 1,615 adults showed that sleep duration was not significantly associated with energy (p=0.84), carbohydrate (p=0.66), fat (p=0.86) or protein (p=0.77) intake after adjusting for body mass index (BMI).

In contrast, an additional hour of sleep was significantly associated with a 0.03-mmol/L (95 percent CI, 0.00 to 0.05; p=0.03) increase in high-density lipoprotein cholesterol (HDL) after adjusting for smoking, socioeconomic status, age, sex and ethnicity.

Additionally, an additional hour of sleep was significantly associated with 0.46-kg/m2 (-0.69 to -0.24; p<0.001) and 0.9-cm (-1.5 to -0.3; p=0.004) reductions in BMI and waist circumference, respectively.

In the unadjusted model, an additional hour of sleep was also significantly associated with a decrease of 0.07 mmol/L (-0.13 to 0.01 mmol/L; p=0.02) in triglyceride levels and of 0.13 (-0.25 to 0.00; p=0.05) in C-reactive protein (CRP) levels.

Sleep duration showed moderate negative associations with levels of fasting glucose (p=0.77), HbA1c (p=0.18), CRP (p=0.85), triglycerides (p=0.38) and free triiodothyronine (p=0.66) after adjusting for BMI, ethnicity, smoking, sex, age and socioeconomic status.

Study participants were enrolled in the National Diet and Nutrition Survey Rolling Programme (NDNS-RP) in the UK study. Those who were pregnant and who had incomplete sleep data were excluded.

Of the participants, 24.8 percent were current smokers, 20.5 percent were ex-smokers and 54.7 percent were nonsmokers. Mean sleep duration for males and females were 7.17±1.15 and 7.22±1.29 hours, respectively.

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Most Read Articles
Yesterday
In patients with rheumatoid arthritis (RA) who are also positive for anticitrullinated protein antibodies (ACPA), tocilizumab (TCZ) treatment for 2 years increases femoral neck bone mineral density (BMD) and decreases concentrations of bone resorption markers, a recent study has found.
3 days ago
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
5 days ago
There appears to be a paradox in the context of smoking and the risk of psoriatic arthritis (PsA), such that current smoking increases the risk of developing PsA in the general population but protects against the same risk among patients with psoriasis, according to a study.
02 Nov 2017
In this issue of MIMS Anti-Infective Supplement, we bring you clinical updates related to combating infectious diseases, and also a symposium highlight in conjunction with the launch of ceftolozane/tazobactam (Zerbaxa; Merck Sharp & Dohme Sdn Bhd) in Malaysia.