Most Read Articles
Roshini Claire Anthony, 5 days ago

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

Stephen Padilla, 6 days ago
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
2 days ago
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Dr. Wong Soon Tee, 6 days ago
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.

Long-term use of double internal stents provides durable relief in EMUO

14 Apr 2020

Use of double internal stents (DIS) in the long term offers durable relief in patients with secondary extrinsic malignant ureteral obstruction (EMUO), reveals a study. DIS avoids the use of external tubes and improves quality of life, making it a valuable alternative to other methods of urinary diversion.

From 2007 to 2019, DIS of 75 renal units were performed in 62 patients (mean age, 60 years; 79 percent female) presenting with EMUO using dwelling 7 FR stents. The investigators conducted surveillance every 3 months. Stents were exchanged routinely every year. Need for permanent stents’ retrieval was deemed a failure.

Risk factors for stent failure and mortality were assessed using univariate and multivariate analyses. Kaplan-Meier estimations provided maintenance of stent patency and disease-specific survival (DSS).

Thirty patients (48 percent) required balloon dilation. The median follow-up was 35.2 months (interquartile range, 26.8–46.7), while the median DSS was 21 months (range, 7.1–45.5). Thirty-nine patients died during the study period, of whom 37 (95 percent) had patent stents in place.

In multivariate analysis, mortality was found to be independently predicted by estimated glomerular filtration rate (eGFR) <60 ml/min/1.73 m2 (hazard ratio [HR], 2.1, 95 percent confidence interval [CI], 1.1–4.2; p=0.02) and balloon dilation (HR, 2.1, 95 percent CI, 1.1–4.1; p=0.02).

Stent failure occurred in six patients (10 percent) due to the following: sepsis, intractable haematuria or creatinine elevation. The mean time to failure was 15 months. Radiation (p=0.038) and eGFR <45 ml/min/1.73 m2 (p=0.001) at presentation independently correlated with stent failure. Forty percent of patients reported stent-related side effects, such as irritative symptoms and haematuria.

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Most Read Articles
Roshini Claire Anthony, 5 days ago

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

Stephen Padilla, 6 days ago
Use of noninvasive ventilation (NIV), similar to invasive mechanical ventilation (IMV), appears to lessen mortality but may increase the risk for transmission of the novel coronavirus disease (COVID-19) in healthcare workers, suggest the results of a study.
2 days ago
Use of corticosteroid is not associated with improved outcomes in idiopathic pulmonary fibrosis (IPF) patients admitted to the hospital with acute exacerbation (AE), reveals a recent study. In addition, corticosteroids may even contribute to reduced overall survival following exacerbation.
Dr. Wong Soon Tee, 6 days ago
Acne is a common skin problem seen in primary care. Dr Wong Soon Tee of Assurance Skin Clinic at Mt Elizabeth Novena Hospital, Singapore shares his insights with Pearl Toh on how to manage acne in the primary care setting.