Most Read Articles
2 days ago
The appropriate cutoff value in predicting combined cardiovascular outcomes in patients with type 2 diabetes (T2D) is 125 mm Hg for home morning systolic blood pressure (MSBP), suggests a new study.
06 Apr 2018

Female patients with coronary artery disease (CAD) have greater regression of coronary atherosclerosis than male patients despite a lower plaque burden at baseline, data from the GLAGOV trial have shown.

26 Apr 2018
Transcatheter aortic valve replacement (TAVR) in severe symptomatic aortic stenosis (AS) patients is superior to conventional surgical aortic valve replacement (SAVR) in terms of reducing life-threatening bleeding, new-onset atrial fibrillation and acute kidney injury, a recent meta-analysis has found.
Pearl Toh, Yesterday
Whether the 2017 ACC/AHA* blood pressure (BP) guidelines should be adopted in Asian countries was the topic of a much-anticipated discussion here at the Asian Pacific Society of Cardiology (APSC) Congress 2018 in Taiwan last week.

Long-term blood pressure variability strongly predicts stroke recurrence

07 Oct 2017

Long-term blood pressure variability (BPV) is more reliable than short-term BPV in predicting stroke recurrence after acute ischaemic stroke or transient ischaemic attack (TIA), a study has shown.

The present investigation included 1,764 patients (mean age 62.45 years; 32.1 percent female; mean body mass index, 24.84 kg m−2) who participated in the BOSS (blood pressure and clinical outcome in transient ischaemic attack [TIA] or ischaemic stroke) study. All patients were examined within 7 days after onset of acute ischemic stroke or TIA.

Short-term BPV was measured using 24-hour ambulatory blood pressure measurement (ABPM) during hospitalization. On the other hand, long-term BPV was determined on the basis of home blood pressure measurement (HBPM), which was taken twice daily by patients or their families from discharge to 90 days after onset of qualifying events. Variability for systolic blood pressure (SBP) was assessed as the SD and coefficients of variance (CV). The clinical outcome was recurrent stroke within 1 year.

During 1-year follow-up, stroke recurrence was reported in 106 (6 percent) patients. Recurrent stroke was significantly associated with indices of long-term BPV (SD: adjusted hazard ratio [aHR], 1.939; 95 percent CI, 1.122 to 3.351; CV: aHR, 1.955; 1.174 to 3.255), independent of mean SBP.

On the other hand, all indices of short-term BPV did not predict stroke recurrence (SD: aHR, 1.245; 0.680 to 2.280; CV: aHR, 1.142; 0.640 to 2.038).

The present data demonstrate that long-term BPV of HBPM is a stronger predictor of stroke recurrence than BPV of ABPM, researchers said.

“Therefore, performing antihypertensive treatment in secondary prevention among patients with ischaemic stroke or TIA further emphasizes the importance of not only achieving but also maintaining stable BP control in the long term,” they added.

Additional prospective studies are needed to investigate how best to measure ABPM in acute ischaemic stroke or TIA, as well as to determine the prognostic significance of measuring ABPM on stroke recurrence.

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Most Read Articles
2 days ago
The appropriate cutoff value in predicting combined cardiovascular outcomes in patients with type 2 diabetes (T2D) is 125 mm Hg for home morning systolic blood pressure (MSBP), suggests a new study.
06 Apr 2018

Female patients with coronary artery disease (CAD) have greater regression of coronary atherosclerosis than male patients despite a lower plaque burden at baseline, data from the GLAGOV trial have shown.

26 Apr 2018
Transcatheter aortic valve replacement (TAVR) in severe symptomatic aortic stenosis (AS) patients is superior to conventional surgical aortic valve replacement (SAVR) in terms of reducing life-threatening bleeding, new-onset atrial fibrillation and acute kidney injury, a recent meta-analysis has found.
Pearl Toh, Yesterday
Whether the 2017 ACC/AHA* blood pressure (BP) guidelines should be adopted in Asian countries was the topic of a much-anticipated discussion here at the Asian Pacific Society of Cardiology (APSC) Congress 2018 in Taiwan last week.