Most Read Articles
6 days ago
Diabetes mellitus (DM) may contribute to complications in head and neck cancer (HNC) patients undergoing concurrent chemoradiotherapy (CCRT), a recent study has found.
Pearl Toh, 14 May 2020
Children with high serum insulin levels and whose parents are under stress are more likely to have asthma symptoms, suggest two studies presented at the AAAAI 2020 Meeting.

Long-term anodal tDCS eases hunger, food intake in obese individuals

03 Jan 2018

Short-term anodal transcranial direct current stimulation (tDCS), a noninvasive technique used to modulate brain activity, appears to confer no immediate effect on ad libitum food intake or weight change compared with sham tDCS, according to a study. However, a longer period of anodal tDCS reduces hunger and snack food intake in obese individuals.

Findings showed that short-term anodal tDCS had no effect on ad libitum food intake from the vending machines relative to sham tDCS. Consequently, there was no effect seen on short-term or 4-week weight change.

Visual analogue scale (VAS) ratings for hunger and the urge to eat significantly decreased more in the anodal tDCS group (p=0.01) vs the sham group (p=0.05). Total energy intake during a snack food taste test (SFTT) was relatively lower in satiated individuals (p=0.01) after long-term tDCS.

Researchers conducted a randomized parallel-design study combining inpatient and outpatient assessments over 31 days. Twenty-three obese individuals (mean body mass index, 39.3 kg/m2; 12 men) received 15 sessions of anodal or sham tDCS aimed at the left dorsolateral prefrontal cortex (DLPFC), a region of the brain that plays a key role in the support of self-regulatory aspects of eating behaviour and inhibitory control.

A vending machine paradigm and SFTTs were used to assess ad libitum food intake. Appetite was estimated using a VAS, and body weight was measured. Researchers then examined the effect of short-term (ie, three sessions) and long-term (ie, 15 sessions) tDCS on these variables.

“Obesity is associated with reduced activation in the left DLPFC,” according to researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Endocrinology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
6 days ago
Diabetes mellitus (DM) may contribute to complications in head and neck cancer (HNC) patients undergoing concurrent chemoradiotherapy (CCRT), a recent study has found.
Pearl Toh, 14 May 2020
Children with high serum insulin levels and whose parents are under stress are more likely to have asthma symptoms, suggest two studies presented at the AAAAI 2020 Meeting.