Most Read Articles
20 Jun 2020
The Lundbeck Neuroscience Symposium was held at Sofitel KL Damansara over 2 days, with extensivediscussions on the management of various mental illnesses. The second day of the symposiumaddressed the topic of schizophrenia management, focusing on treatment goals, the rationale forpartial dopamine D(2) receptor agonism and the use of long-acting injectable (LAI) antipsychotics topromote adherence.
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Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
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Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
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Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.

Loneliness in COPD patients related to worse health perceptions, increased ED visits

08 Sep 2019

Patients with chronic obstructive pulmonary disease (COPD) who feel lonely and socially isolated are more likely to visit the emergency department (ED), with their perceived health status being poor, a study has shown.

Researchers looked at 1,217 patients (mean age, 65 years; 47 percent female) with moderate-to-severe COPD who participated in the National Emphysema Treatment Trial (NETT).  Mean forced expiratory volume in 1 second (FEV1)% predicted was 41.

Of the patients who completed the Quality of Wellbeing questionnaires, which asked about loneliness and social isolation, 96 (7.9 percent) reported feeling lonely. These patients were more likely to be women (11 percent vs 6 percent) and have lower 6-minute walk test (6MWT) distances, poorer overall health ratings and increased breathlessness.

Logistic regression analysis revealed loneliness to be significantly associated with increased healthcare utilization, as represented by the likelihood of visiting the ED in the 5 years of follow-up. Relative to those who were not lonely, patients who felt lonely were about 50-percent more likely to make an ED visit (odds ratio [OR], 1.57, 95 percent CI, 1.005–2.466; p=0.04).

Furthermore, loneliness negatively affected the overall perception of general health (p0.0001), with lonely patients having health ratings of 9.9 points lower than those of other patients.

In light of the present data, the researchers called for frequent assessment of loneliness in COPD patients in routine practice. They believe that addressing loneliness in the outpatient setting may ultimately contribute to reducing ED visits and improved quality of life in this population.

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Most Read Articles
20 Jun 2020
The Lundbeck Neuroscience Symposium was held at Sofitel KL Damansara over 2 days, with extensivediscussions on the management of various mental illnesses. The second day of the symposiumaddressed the topic of schizophrenia management, focusing on treatment goals, the rationale forpartial dopamine D(2) receptor agonism and the use of long-acting injectable (LAI) antipsychotics topromote adherence.
Pearl Toh, 5 days ago
Having migraine during midlife appears to be associated with a higher risk of developing dementia in later life, according to a large population-based longitudinal Danish study presented at the AHS* 2020 Virtual Meeting, indicating that migraine may be a risk factor for dementia.
4 days ago
Patients with psoriatic arthritis (PsA) often suffer from liver abnormalities, which are associated with higher body mass index (BMI), daily consumption of alcohol, more severe disease, and some therapies, according to a recent study.
Christina Lau, 3 days ago

Pembrolizumab in combination with chemotherapy significantly improves progression-free survival (PFS) vs chemotherapy alone in patients with previously untreated, locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC), results of the KEYNOTE-355 study have shown.