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Roshini Claire Anthony, 4 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.

LDL, total cholesterol predict new-onset atrial fibrillation in ASTEMI patients

09 Nov 2019

In patients with acute ST-segment elevation myocardial infarction (ASTEMI), the risk of new-onset atrial fibrillation (NOAF) appears to be linked with plasma levels of low-density lipoprotein cholesterol (LDL-C) and total cholesterol (TC), a recent China study has found.

Of the 985 ASTEMI patients (mean age, 63.4±12.6 years; 79.9 percent male) enrolled, 81 developed NOAF over 31 months of observation. The resulting incidence rate was 8.2 percent. These patients tended to present with significantly lower LDL-C, TC and triglyceride concentrations.

Multivariable logistic regression analysis found that, when grouped into tertiles of lipid concentrations, participants in the middle (odds ratio [OR], 0.46, 95 percent confidence intervals [CI], 0.22–0.98; p=0.044) and topmost (OR, 0.24, 95 percent CI, 0.1–0.58; p=0.002; p-trend=0.004) categories of TC benefited from significant protection against NOAF.

A similar and significant (p=0.001) trend was observed for LDL-C (middle tertile: OR, 0.23, 95 percent CI, 0.10–0.53; p=0.001; top tertile: OR, 0.38, 95 percent CI, 0.17–0.83; p=0.015).

In contrast, triglyceride levels and concentrations of high-density lipoprotein cholesterol were unrelated to the risk of developing NOAF.

In terms of outcomes, NOAF patients had an all-cause mortality rate of 19.8 percent. Kaplan-Meier analysis found that this was significantly higher than that in the sinus rhythm comparators (6.1 percent; log-rank p<0.001). Cardiogenic shock was likewise greater (17.3 percent vs 6.6 percent; p<0.001) and hospital stay was longer (10.1±5.3 vs 8.3±4.7 days; p=0.002) in the NOAF group.

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Most Read Articles
Roshini Claire Anthony, 4 days ago

The presence of pulmonary arterial hypertension (PAH) in individuals with systemic sclerosis is associated with an increased mortality risk, a study from Singapore showed.

23 Dec 2019
At a Menarini-sponsored symposium held during the Asian Pacific Society Congress, renowned cardiologist Prof John Camm provided the latest evidence for chronic stable angina with or without concomitant diseases, with a special focus on the antianginal agent ranolazine and combination therapies. The event was chaired and moderated by Dr Dante Morales from the University of the Philippines College of Medicine.
3 days ago
Serum 25-hydroxyvitamin D (25[OH]D) levels are significantly lower among patients with active uveitis than those with inactive uveitis and local population-based estimates, reports a study. In addition, vitamin D supplementation may help reduce uveitis activity, while sun exposure confers a beneficial effect to those with vitamin D deficiency.
2 days ago
The timing of direct oral anticoagulants (DOACs) administration, either within 3 days or ≥4 days of stroke onset, in patients with nonvalvular atrial fibrillation (AF) does not alter the risk of adverse outcomes such as stroke or systemic embolism, major bleeding, and death, as shown in a recent study.