Most Read Articles
15 Sep 2016
Tigecycline therapy produces favourable outcomes in severe Clostridium difficile infection (sCDI), says a study.
Roshini Claire Anthony, 22 May 2018

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Pearl Toh, 28 Dec 2017
The addition of low oxygen levels measured by pulse oximetry to the three signs delineated in the current diagnostic model for pneumonia in primary care setting derived by van Vugt, which include fever, tachycardia, and crackly breath sounds on auscultation, can add value to diagnostic precision and help general practitioners (GPs) differentiate pneumonia from less serious infections, a study suggests.
26 Sep 2017
Ceftazidime-avibactam appears to offer a reasonable alternative to colistin in the treatment of Klebsiella pneumoniae carbapenemase (KPC)-producing carbapenem-resistant Enterobacteriaceae (CRE) infections, according to a study.

Latest quadrivalent vaccine joins list of available flu vaccine

Dr Joslyn Ngu
04 Dec 2017

A quadrivalent influenza vaccine consisting of H1N1, H3N2, B-Yamagata and B-Victoria strains is now available locally.

“Influenza viruses are constantly changing, which is why it is possible to catch the flu more than once. Annual vaccination, particularly around flu season, is a way to protect yourself, family and friends, said Dr Rupert Jakes, Medical Affairs Director, Vaccines, GlaxoSmithKline (GSK) Pharmaceutical Sdn Bhd, Malaysia. By targeting four flu strains, this new vaccine can provide better protection than its trivalent predecessors, he said.

Flu can be a severe condition, particularly if it occurs in more vulnerable patients, said Professor Yasmin Malik, visiting senior clinical consultant, University Malaya Medical Centre. Even if the patient is not hospitalized, he can develop serious complications such as heart attack and stroke. With the availability of flu vaccines, the risk of serious complications can be reduced.

In temperate countries, the incidence of influenza rises in the winter because of virus mutations, and preference for cold and dry weather conditions, said Yasmin. Meanwhile, in tropical countries like Malaysia, influenza occurs year-round with no seasonal trends. However, there is an increase in infections during rainy seasons.

Elaborating on influenza statistic in the country, she said serosurveillance using molecular tests showed that influenza viruses were detected in 13 percent of respiratory samples obtained from patients with influenza-like illness. This suggests that the incidence of the virus infection is underestimated.

Influenza can lead to serious complications, particularly in pregnant women, children between the ages of 6 and 59 months, the elderly—above the age of 64, those with weakened immune systems, healthcare professionals and those with specific medical conditions such as asthma and chronic heart disease, said Yasmin.

Complications that may occur include Guillain-Barre syndrome, acute viral encephalitis in children, Reye’s syndrome in children, increased risk of heart attack and stroke, and pneumonia.

The vaccine is an inactivated influenza vaccine that is indicated for adults, and children above the age of 2. It has been shown to be well-tolerated in children, adults and the elderly. The vaccine is to be administered intramuscularly, preferably in the deltoid or anterolateral thigh muscles.

Yasmin and Jakes were speaking at the media launch of Fluarix Tetra by GSK, held recently in Kuala Lumpur.

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Most Read Articles
15 Sep 2016
Tigecycline therapy produces favourable outcomes in severe Clostridium difficile infection (sCDI), says a study.
Roshini Claire Anthony, 22 May 2018

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Pearl Toh, 28 Dec 2017
The addition of low oxygen levels measured by pulse oximetry to the three signs delineated in the current diagnostic model for pneumonia in primary care setting derived by van Vugt, which include fever, tachycardia, and crackly breath sounds on auscultation, can add value to diagnostic precision and help general practitioners (GPs) differentiate pneumonia from less serious infections, a study suggests.
26 Sep 2017
Ceftazidime-avibactam appears to offer a reasonable alternative to colistin in the treatment of Klebsiella pneumoniae carbapenemase (KPC)-producing carbapenem-resistant Enterobacteriaceae (CRE) infections, according to a study.