Lactobionic acid effective for acne vulgaris
Peeling treatments with lactobionic acid, corundum microdermabrasion, or a combination of both can significantly decrease sebum secretion in patients with acne vulgaris, a new study finds.
Of the three treatments, peeling with lactobionic acid alone produced the best result followed by the combination treatment. The least effective method was the treatment with corundum microdermabrasion alone.
In the experiment, researchers recruited 45 female participants which were divide into three groups of 15. Patients had suffered low to medium grade acne intensity according to Cunliffe’s scale. They had not been treated for 3 months prior. Other than acne and elevated sebum levels, patients had no other facial skin changes.
A Sebumeter SM15 was used to measure the levels of grease on the skin of the forehead, cheeks, nose, and chin of each participant. Measurements were collected before each treatment session, 5 times over the course of 2 weeks. A final measurement was collected 2 weeks after the last treatment.
Prior to treatments, the patients’ faces were purified using a gel and left for 5 hours without any cream use. A 50 percent lactobionic acid treatment was used and applied to the face for 20 minutes before washing with water, drying, and treating with moisturising cream.
The corundum microdermabrasion process was performed after facial degreasing. The exfoliation was performed 3 times over 10 minutes after which the face was washed and a moisturising cream was applied.
In the combination treatment, corundum microdermabrasion was performed before using the 50 percent lactiobionic acid.
By the second or third treatment, the levels of sebum in the patients’ faces strongly dropped regardless of the treatment used. However, the chemabrasion treatment with 50 percent lactobionic acid yielded the greatest decrease in sebum secretion. The combined treatment and corundum microdermabrasion were second and third respectively.
The results imply that any of the experimental skin treatments may bring about significant drops in sebum secretion levels in faces of acne vulgaris patients. For future studies, researchers recommend tighter controls, especially in application pressure and duration, to better see and understand this relationship.