Most Read Articles
Rachel Soon, 16 Aug 2019

On 8 August, the first town hall held by the Ministry of Health (MOH) with members of the pharmacy profession took place in Putrajaya. Over 500 pharmacists from across the country and from different areas of practice—community and hospital, public and private, academy and industry—converged to fill the auditorium for the chance to engage in direct dialogue with MOH.

3 days ago
Cardiac biomarkers are useful for identifying community-acquired pneumonia (CAP) patients with an elevated risk of early and long-term cardiovascular (CV) events, according to a study.
Yesterday
Tofogliflozin is safe and effective for elderly patients with type 2 diabetes mellitus (T2DM), regardless of insulin and oral antidiabetic drugs, reports a new Japan study.
6 days ago
Pulmonary function has potential predictive value for future increases in arterial stiffness and its progression, as reported in a recent study.

Kids with Crohn’s disease tolerate an exclusion diet with PEN better than EEN

08 Aug 2019
Among the 20 child or youth suicide cases, 14 persons jumped from height to their death, with the youngest one aged only 11.

For children with mild-to-moderate Crohn’s disease (CD), a CD exclusion diet (CDED) combined with partial enteral nutrition (PEN) is more tolerable than exclusive enteral nutrition (EEN), a recent study has found.

Researchers randomly assigned 74 children with mild-to-moderate CD to undergo diet regimens involving either CDED with 50 percent of calories from formula followed by CDED with 25 percent PEN (group 1; n=40; mean age, 13.8±2.8 years; 65 percent male) or EEN followed by free diet with 25 percent PEN (group 2; n=38; mean age, 14.5±2.6 years; 59 percent male). The overall duration of the trial was 12 weeks, with each phase lasting 6 weeks.

Tolerance to the diet, measured according to withdrawals due to refusal to continue the trial, was significantly better in group 1 (97.5 percent vs 73.7 percent; p=0.002). Children assigned to the CDED+PEN diet were more likely to complete the trial than their EEN counterparts (odds ratio [OR], 13.92, 95 percent CI, 1.68–115.14).

In terms of secondary endpoints, researchers recorded no significant between-group difference in terms of response rate (CDED+PEN vs EEN: 85 percent vs 85.3 percent; p=0.97; OR, 0.97, 0.27–3.53) and corticosteroid-free remission (80 percent vs 73.5 percent; p=0.51; OR, 1.44, 0.49–4.27).

Both dietary interventions also resulted in significant improvements from baseline in inflammatory markers, scores in the paediatric CD activity index and mean weight z-scores. Between-group comparisons did not result in statistically significant figures.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Rachel Soon, 16 Aug 2019

On 8 August, the first town hall held by the Ministry of Health (MOH) with members of the pharmacy profession took place in Putrajaya. Over 500 pharmacists from across the country and from different areas of practice—community and hospital, public and private, academy and industry—converged to fill the auditorium for the chance to engage in direct dialogue with MOH.

3 days ago
Cardiac biomarkers are useful for identifying community-acquired pneumonia (CAP) patients with an elevated risk of early and long-term cardiovascular (CV) events, according to a study.
Yesterday
Tofogliflozin is safe and effective for elderly patients with type 2 diabetes mellitus (T2DM), regardless of insulin and oral antidiabetic drugs, reports a new Japan study.
6 days ago
Pulmonary function has potential predictive value for future increases in arterial stiffness and its progression, as reported in a recent study.