Most Read Articles
Yesterday
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
3 days ago
There appears to be a paradox in the context of smoking and the risk of psoriatic arthritis (PsA), such that current smoking increases the risk of developing PsA in the general population but protects against the same risk among patients with psoriasis, according to a study.
4 days ago
Moderate increases in physical activity levels may translate to significant reductions in both fasting glucose and HbA1c, a study has found.
Pearl Toh, 14 Nov 2017
Performing percutaneous coronary intervention (PCI) on culprit lesion only, rather than a multivessel PCI, reduces the 30-day composite risk of death or severe renal failure in patients with acute myocardial infarction (MI) complicated by cardiogenic shock and multivessel disease, according to the CULPRIT-SHOCK* study presented at the TCT 2017 Congress held in Denver, Colorado, US.

Isolated maternal hypothyroxaemia in third trimester linked to pre-eclampsia

14 Jul 2017
Researchers in China have shown that isolated maternal hypothyroxaemia (IMH) detected during the third trimester of pregnancy is strongly correlated with pre-eclampsia in the first large-scale investigation to undertake long-term monitoring of free thyroxin (FT4) levels in Chinese mothers with hypothyroxaemia.

In the study, first (week 9–12) and third (week 32–36) trimester serum samples were collected from 6,031 mothers (aged 21–43 years) for analyses of thyroid function. All of the women had singleton pregnancies, were Han Chinese, had no history of thyropathy or autoimmune disease, no goiters, were thyroid peroxidase antibody (TPOAb)-negative, and did not use medicines that would affect thyroid hormone levels. In addition, all had TSH levels within the reference intervals during the first and third trimesters of pregnancy. Women were monitored for adverse pregnancy outcomes such as gestational diabetes mellitus (GDM), pregnancy-induced hypertension, and pre-eclampsia.

The researchers found that women who were older and those who had a higher pre-pregnancy body mass index were more likely to experience hypothyroidism. Although pregnancy-induced hypertension was not significantly correlated with FT4, GDM, and pre-eclampsia were inversely correlated with maternal FT4 levels during early and late pregnancy, respectively. In particular, women with IMH during the third trimester had an increased risk of developing pre-eclampsia.
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Most Read Articles
Yesterday
Long-term use of benzodiazepines is independently associated with lower diastolic and systolic blood pressure in ambulatory blood pressure monitoring (ABPM) among older but not younger patients, a study has found.
3 days ago
There appears to be a paradox in the context of smoking and the risk of psoriatic arthritis (PsA), such that current smoking increases the risk of developing PsA in the general population but protects against the same risk among patients with psoriasis, according to a study.
4 days ago
Moderate increases in physical activity levels may translate to significant reductions in both fasting glucose and HbA1c, a study has found.
Pearl Toh, 14 Nov 2017
Performing percutaneous coronary intervention (PCI) on culprit lesion only, rather than a multivessel PCI, reduces the 30-day composite risk of death or severe renal failure in patients with acute myocardial infarction (MI) complicated by cardiogenic shock and multivessel disease, according to the CULPRIT-SHOCK* study presented at the TCT 2017 Congress held in Denver, Colorado, US.