Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Isolated maternal hypothyroxaemia in third trimester linked to pre-eclampsia

14 Jul 2017
Researchers in China have shown that isolated maternal hypothyroxaemia (IMH) detected during the third trimester of pregnancy is strongly correlated with pre-eclampsia in the first large-scale investigation to undertake long-term monitoring of free thyroxin (FT4) levels in Chinese mothers with hypothyroxaemia.

In the study, first (week 9–12) and third (week 32–36) trimester serum samples were collected from 6,031 mothers (aged 21–43 years) for analyses of thyroid function. All of the women had singleton pregnancies, were Han Chinese, had no history of thyropathy or autoimmune disease, no goiters, were thyroid peroxidase antibody (TPOAb)-negative, and did not use medicines that would affect thyroid hormone levels. In addition, all had TSH levels within the reference intervals during the first and third trimesters of pregnancy. Women were monitored for adverse pregnancy outcomes such as gestational diabetes mellitus (GDM), pregnancy-induced hypertension, and pre-eclampsia.

The researchers found that women who were older and those who had a higher pre-pregnancy body mass index were more likely to experience hypothyroidism. Although pregnancy-induced hypertension was not significantly correlated with FT4, GDM, and pre-eclampsia were inversely correlated with maternal FT4 levels during early and late pregnancy, respectively. In particular, women with IMH during the third trimester had an increased risk of developing pre-eclampsia.
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Most Read Articles
Roshini Claire Anthony, 4 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

Tristan Manalac, 19 May 2018
Taking oral antibiotics appears to increase the risk of nephrolithiasis, according to a recent study. Moreover, the risk seems to be compounded for individuals with recent antibiotic exposure and those who were exposed at a younger age.
2 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
3 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.