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17 Jul 2018
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Is there a link between phosphorus intake and blood pressure?

6 days ago

There appears to be no consistent association between total dietary phosphorus intake and blood pressure (BP) in adults in previous studies or in any randomized trial designed to examine this association, a recent systematic review has found.

The investigators included randomized and nonrandomized behavioural intervention and feeding studies (intervention studies), as well as prospective observational studies that measured dietary phosphorus intake or urinary phosphorus excretion and BP. Studies of supplements, children or individuals with major medical conditions were excluded.

PubMed, Embase, Cochrane Trials and clinicaltrials.gov were searched on 1 June 2017 and 22 August 2018. Risk of bias in the assessment of phosphorus exposure and BP was assessed in the studies. A total of 4,759 publications were reviewed, with 14 intervention studies (n=2,497 participants), three prospective observational cohorts (n=17,795) and two ongoing trials included. There were no intervention studies specifically designed to achieve a phosphorus contrast.

In two studies, dietary phosphorus had a significant positive association with systolic BP, while a significant inverse association was found in four studies. On the other hand, eight studies did not find a significant association. In four studies, dietary phosphorus was inversely associated with diastolic BP, while 10 studies found no significant associations.

Furthermore, the risk of incident hypertension was lower comparing the highest with the lowest quintiles of phosphorus intake in two cohorts, whereas one found no significant difference (hazard ratio [HR], 0.86; 0.75–0.98; HR, 0.83; 0.68–1.02; HR, 0.75; 0.45–1.27, respectively).

“Elevated BP is a major cause of preventable disease in the United States and around the world,” the investigators said. “It has been postulated that phosphorus intake may affect BP, with some studies suggesting a direct and others an inverse association.”

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Most Read Articles
17 Jul 2018
Higher total intake of dairy products, especially yogurt, may help reduce the risk of incident hypertension in middle-aged and older adult men and women, suggests a recent study.
19 Oct 2016
A new system called Preoperative Evaluation Clinic (PEC) workflow for cardiothoracic surgery significantly reduced the cancellation rate of elective cases at the National Heart Centre Singapore (NHCS), according to a study presented at the ASEAN Federation of Cardiology Congress (AFCC) 2016 in Yangon, Myanmar.
Pearl Toh, 19 Dec 2018
A structured cardiovascular (CV) exercise programme during adjuvant breast cancer treatment provides significant protection against decline in CV function related to chemotherapy-induced cardiotoxicity, according to the EBBA*-II trial presented at SABCS 2018, indicating that physical activity during treatment for breast cancer can benefit patients.
Rachel Soon, 31 Jan 2019

Despite increased availability of treatment options, hypertension and associated comorbidities remain a substantial public health concern, says an expert.