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01 Mar 2015
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Iron supplements may reduce SBP in LBW children at 7 years

07 Aug 2017
Nurse moms who feel more equipped in managing their children’s moods will create a happier environment for them to thrive in.

Iron supplementation (1 or 2 mg Fe · kg−1· d−1) in low birth weight (LBW) children during infancy is associated with lower systolic blood pressure (SBP) at 7 years, a recent study has found.

To examine the effect of iron supplementation given to LBW infants on midchildhood BP, researchers conducted a randomized, double-blind, controlled trial including 285 marginally LBW (2,000 to 2,500 g) infants at two Swedish centres between May 2004 and November 2007.

Participants were randomly assigned to receive either placebo or 1 or 2 mg Fe · kg−1 · d−1 from 6 weeks to 6 months of age. Researchers then compared SBP, diastolic (D)BP and the prevalence of children with BP within the hypertensive range (>90th percentile) between the groups in secondary analyses at the age of 7 years.

Intention-to-treat analysis of BP was performed in 189 children (66 percent).

LBW children who received placebo (n=70), 1 mg Fe · kg−1 · d−1 (n=54) or 2 mg Fe · kg−1 · d−1 (n=65) had mean SBP of 103±8.1, 101±7.5 and 101±7.8 mm Hg, respectively. Combining the iron-supplemented group in covariate-adjusted analyses showed that children who received iron supplementation in infancy had a mean SBP of 2.2 mm Hg (95 percent CI, 0.3 to 4.2 mm Hg) lower than in those who did not receive supplementation (p=0.026).

Based on multivariate logistic regression analysis, the odds of having an SBP within the hypertensive range at the age of 7 years were reduced with iron supplementation in infancy (odds ratio, 0.32; 0.11 to 0.96). No significant differences in DBP were observed between the intervention groups.

“This novel observation [to our knowledge] suggests that the increased risk of hypertension that is observed in children and adults who are born small might be reduced with early micronutrient interventions,” researchers said.

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Most Read Articles
01 Mar 2015
Red yeast rice extracts have been used in traditional medicine for centuries.1 In recent times, an extract from red yeast rice, Xuezhikang® (XZK), has been studied for its role in dyslipidaemia and cardiovascular disease. This review will look at some of the clinical trials that have done so.
13 Jun 2017
Both haemorrhagic and ischaemic stroke patients benefit similarly from a conventional therapy combined with robotic-assisted gait training (RAGT) intervention regimen, a new study shows.
30 Jun 2016
Perindopril can protect patients with paroxysmal atrial fibrillation (AF) from recurrence after radiofrequency catheter ablation, as stated in a study.
4 days ago
Enriching salt with both potassium and magnesium in the long term may provide additional benefits for stroke patient recovery from neurologic deficits, suggests a recent study involving Taiwanese patients.