Most Read Articles
14 Feb 2020
Chronic pancreatitis patients taking antioxidants (AO) supplementation show a sustained increase in blood levels of AO, but no additional benefit is seen on endocrine and exocrine functions, markers of fibrosis, oxidative stress (OS) and inflammation, nutritional status, pain, and quality of life (QOL) when compared with those on placebo, according to a study.
Roshini Claire Anthony, 12 Feb 2020

Children with inflammatory bowel disease (IBD) do not appear to have an elevated risk of lymphoma following treatment with anti-tumour necrosis factor (TNF) agents, according to a study presented at the recent Crohn’s and Colitis Congress 2020.

Jairia Dela Cruz, 3 days ago
A diet low in fat and high in fibre seems well tolerated in patients with ulcerative colitis, not contributing to increased inflammation while significantly increasing populations of Faecalibacterium prausnitzii, according to a study presented at the 2020 Crohn's & Colitis Congress.
Pearl Toh, 14 Feb 2020
Donor selection for faecal microbiota transplant (FMT) can make a difference to maintenance of long-term remission in patients with ulcerative colitis (UC), reveals a study presented at the 2020 Crohn's & Colitis Congress (CCC).

Intestinal ultrasound useful for evaluating disease, therapeutic response in UC

09 Feb 2020

Intestinal ultrasound is useful in monitoring disease course and evaluating short-term treatment response in patients with ulcerative colitis (UC) and may serve as a viable point-of-care tool in general practice, according to data from the TRUST&UC* study.

TRUST&UC enrolled 253 consecutive patients with a diagnosis of a proctosigmoiditis, left-sided colitis or pancolitis currently in clinical relapse (defined as Short Clinical Colitis Activity Index [SCCAI] ≥5).

A total of 224 patients (88.5 percent) had an increased bowel wall thickness (BWT) in the descending or sigmoid colon at baseline, as assessed using duplex/Colour Doppler ultrasonography. Of these, half had a left-sided colitis while the other half had a pancolitis.

The number of patients with an increased BWT in the sigmoid or descending colon decreased significantly within the first 2 weeks of the study, from 89.3 percent to 38.6 percent and from 83.0 percent to 42.9 percent (p-both<0.001), respectively. This remained low at weeks 6 and 12 (sigmoid colon: 35.4 percent and 32.0 percent; descending colon: 43.4 percent and 37.6 percent; p<0.001).

BWT normalization and clinical response following 12 weeks of treatment were strongly correlated, such that 90.5 percent of patients with normalized BWT had symptomatic response (p<0.001).

The present data provide evidence that monitoring BWT alone has the potential to predict the therapeutic response, which should be verified in future studies, according to researchers.

*The study TRansabdominal Ultrasonography of the bowel in Subjects with IBD To monitor disease activity with UC

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Most Read Articles
14 Feb 2020
Chronic pancreatitis patients taking antioxidants (AO) supplementation show a sustained increase in blood levels of AO, but no additional benefit is seen on endocrine and exocrine functions, markers of fibrosis, oxidative stress (OS) and inflammation, nutritional status, pain, and quality of life (QOL) when compared with those on placebo, according to a study.
Roshini Claire Anthony, 12 Feb 2020

Children with inflammatory bowel disease (IBD) do not appear to have an elevated risk of lymphoma following treatment with anti-tumour necrosis factor (TNF) agents, according to a study presented at the recent Crohn’s and Colitis Congress 2020.

Jairia Dela Cruz, 3 days ago
A diet low in fat and high in fibre seems well tolerated in patients with ulcerative colitis, not contributing to increased inflammation while significantly increasing populations of Faecalibacterium prausnitzii, according to a study presented at the 2020 Crohn's & Colitis Congress.
Pearl Toh, 14 Feb 2020
Donor selection for faecal microbiota transplant (FMT) can make a difference to maintenance of long-term remission in patients with ulcerative colitis (UC), reveals a study presented at the 2020 Crohn's & Colitis Congress (CCC).