Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.

Intercalary allografts reliable for reconstruction after bone tumour excision

15 Sep 2017

Intercalary allografts enhanced with intramedullary cement and compression plate fixation are reliable as a reconstruction method following primary diaphyseal bone tumour excision, a new single-centre study has found. Moreover, the method yields high satisfaction and functional outcomes.

Analysis of the 46 patients (mean age 32.8 years) who received intercalary allografts between 1989 and 2014 revealed a median graft survival time of 92 months and an overall intercalary allograft survival rate of 84.8 percent.

Complications were reported in 33 percent (n=15) of the patients; 13 required surgical interventions, while the remaining two were managed without operations. Three patients experienced nonunion of grafts, one of which was treated with an autograft. The mean time to union was 9 months. Fracture of the allograft was reported in two patients.

Local recurrence after treatment of bone sarcoma was reported in only 8.7 percent (n=4) of the patients. One of the patients also had recurrent tumour in the tibia and needed below-knee amputation.

In terms of functional outcomes, only 70 percent (n=32) of the patients had complete information. The mean Musculoskeletal Tumour Society (MSTS) 87 score of these patients was 29.1±4.5. By comparison, the mean MSTS 93 and Toronto Extremity Salvage Score (TESS) ratings were 82.2±15.7 and 81.2±16.8, respectively.

Functional outcomes were the best for patients who received humeral reconstruction. Similarly, functional scores were significantly better for the upper limbs based on the TESS scores (p=0.03). Differences in the MSTS 87 (p=0.11) and MSTS 93 (p=0.14) scores were only marginally significant.

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Most Read Articles
2 days ago
Dairy consumption during adolescence or early adulthood does not appear to be associated with the overall risk of breast cancer, although results vary by hormone receptor status of tumours, a study has shown. Specifically, dairy intake is linked to higher ER–/PR– and lower ER+/PR+ cancer risk.
Roshini Claire Anthony, 5 days ago

The combined use of piperacillin and tazobactam does not appear to be a suitable alternative to meropenem for patients with bloodstream infections caused by ceftriaxone-resistant Escherichia coli (E. coli) or Klebsiella pneumoniae (K. pneumoniae), according to results of the MERINO* trial.

3 days ago
Patients with inflammatory bowel disease are at increased risk of developing acute myocardial infarction (AMI) or heart failure, although the prevalence of traditional risk factors for such cardiovascular disorders appears to be low, as reported in a recent study.
4 days ago
Early renin-angiotensin-aldosterone system (RAAS) blockade with renin-angiotensin system inhibitors (RASI) leads to better short- and long-term renal outcomes in systemic lupus erythematosus (SLE) patients with antiphospholipid-associated nephropathy (aPLN), according to a study, adding that this renal protective effect is independent of RASI’s antihypertensive and antiproteinuric effects.