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Ivermectin confers benefits in the treatment of COVID-19, with a recent study showing that its use helps reduce the risk of death especially in patients with severe pulmonary involvement.
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Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Tristan Manalac, 5 days ago
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Integrated telerehabilitation approach eases motor symptoms in multiple sclerosis

07 Oct 2020

An integrated telerehabilitation approach (ITA) confers benefits to individuals with multiple sclerosis (MS) in the treatment of motor symptoms according to the current model of continuity of care, reports a recent study.

“However, the low efficacy of ITA on cognition and participation domains suggests the necessity to develop intervention models that include a broader spectrum of needs and objectives,” the investigators said.

A systematic search was performed for original manuscripts focusing on ITA in MS patients. Efficacy on motor, cognitive, and participation outcomes were measured as the standardized mean difference (Hedges’ g) of pre- and post-training.

Nine studies, including a total of 716 MS patients, met the eligibility criteria. The overall effect of ITA was large for motor outcomes (g, 1.05; p=0.013), small for cognitive performance outcomes (g, 0.16; p=0.237), and small for participation outcomes (g, 0.15; p=0.259).

Domain-specific results demonstrated large effect on motor disability (g, 1.18) and medium effect on gait (g, 0.32) and balance (g, 0.48). In addition, all effects on single cognitive domains were small. Among the single participation outcomes considered (ie, depression fatigue, daily functioning, quality of life, and self-efficacy), only depression had a nearly medium effect (g, 0.30).

“MS is a chronic immune-mediated disease of the central nervous system and a major cause of disability in young adults,” the investigators said. “Recently, there has been a growing interest in the development of innovative ways to deliver rehabilitation care outside of a hospital setting.”

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Most Read Articles
2 days ago
Ivermectin confers benefits in the treatment of COVID-19, with a recent study showing that its use helps reduce the risk of death especially in patients with severe pulmonary involvement.
Yesterday
Mental health comorbidities are common among patients with type 2 diabetes mellitus and may lead to worse outcomes, a recent study has found.
Roshini Claire Anthony, 13 Nov 2020

Diabetes is a key risk factor for heart failure (HF), which is the leading cause of hospitalization in patients with or without diabetes. SGLT-2* inhibitors (SGLT-2is) have been shown to reduce the risk of hospitalization for HF (HHF) regardless of the presence or absence of diabetes.

Tristan Manalac, 5 days ago
The substitution of isoleucine to leucine at amino acid 97 (I97L) in the core region of the hepatitis B virus (HBV) seems to reduce its potency, decreasing the efficiency of both infection and the synthesis of the virus’ covalently closed circular (ccc) DNA, reports a new study presented at The Liver Meeting Digital Experience by the American Association for the Study of Liver Diseases (AASLD 2020).