Insomnia tied to metabolic syndrome in males, middle-aged adults
Insomnia is independently correlated with metabolic syndrome in males and in middle-aged adults, a new cross-sectional study in a Chinese population has found.
Investigators grouped 8,017 adults (mean age 42.08±12.95 years; 51.79 percent male) into three age groups: <40 years (young adult group; n=3,927), 40 to 59 years (middle-aged group; n=3,150) and >60 years (older group; n=940). The corresponding prevalence of metabolic syndrome in the age groups were 19.79, 35.37 and 52.13 percent. The overall prevalence was 29.70 percent.
In both the crude (odds ratio [OR], 1.39; 95 percent CI, 1.21 to 1.59; p<0.01) and age- and gender-adjusted models (OR, 1.18; 1.02 to 1.37; p=0.03), insomnia was significantly associated with metabolic syndrome.
However, after additional adjustments for education, income, salt intake, body mass index, smoking, physical activity and drinking, the significant association was attenuated (OR, 1.18; 0.98 to 1.41; p=0.08).
Further analyses showed that, after pertinent adjustments, insomnia was significantly associated with metabolic syndrome only in males (OR, 1.35; 1.02 to 1.77; p=0.03) and in the middle-aged group (OR, 1.40; 1.09 to 1.79; p=0.01).
When individual components of metabolic syndrome were studied, researchers found that insomnia was significantly associated only with higher blood pressure (OR, 1.22; 1.05 to 1.43; p=0.01) and lower high-density lipoprotein cholesterol (OR, 1.16; 1.01 to 1.33; p=0.04).
In all participants, insomnia showed significant associations with the severity of metabolic abnormalities (OR, 1.17; 1.03 to 1.32; p=0.01) after appropriate adjustments for potential confounders.