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Tristan Manalac, 16 May 2018
Although the conversion rate of ocular (OMG) to generalized (GMG) myasthenia gravis in Asian patients is low, thymoma and acetylcholine receptor (AchR) antibodies as well as positivity in repetitive nerve stimulation (RNS) studies all predict such generalization, a recent Singapore study has shown.

Injuries, hospital transfers up risk of 14-day rehospitalization after tSCI

04 Sep 2017

Delayed traumatic spinal cord injury (tSCI) diagnoses, interhospital transfers and injuries in the chest, brain and abdominal area are risk factors for 14-day rehospitalization with new tSCI, a recent study has shown.

Of the 23,617 patients with initial tSCI, 997 were rehospitalized within 14 days for new tSCI, yielding an incidence rate of 4.22 percent. The remaining 22,620 were designated as the control group. Matching at a 1:4 ratio resulted in a total of 4,985 patients, 997 of which were cases while 3,988 were controls.

In the multiple logistic regression analysis, interhospital transfer (odds ratio [OR], 8.20; 95 percent CI, 6.48 to 10.38; p<0.0001) significantly increased the risk of 14-day rehospitalization. In contrast, high disease severities (OR for injury severity score [ISS] 16 to 24, 0.17; 0.13 to 0.21; p<0.0001; OR for ISS >24 OR, 0.11; 0.07 to 0.18; p<0.0001) were associated with significantly lower risks of rehospitalization.

Associated injuries in the brain (OR, 2.82 2.36 to 3.37; p<0.0001), chest (OR, 2.99; 2.14 to 4.19; p<0.0001) and abdomen (OR, 2.74; 1.62 to 4.62; p=0.0002) also significantly increased the risk of 14-day rehospitalization.

Similarly, injuries in the thoracic (OR, 1.62; 1.21 to 2.18; p=0.0012), lumbar (OR, 1.30; 1.02 to 1.65; p=0.0352) and multiple (OR, 3.23; 1.86 to 5.61; p<0.0001) levels also raised the 14-day rehospitalization risk compared with injuries at the cervical level.

Other risk factors included hospitalization in the orthopaedic department (OR, 2.26; 1.78 to 2.87; p<0.0001), motor vehicle collision injuries (OR, 1.36; 1.12 to 1.65; p=0.0019) and pelvic injuries (OR, 1.84; 1.02 to 3.32; p=0.0427).

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Most Read Articles
Tristan Manalac, 16 May 2018
Although the conversion rate of ocular (OMG) to generalized (GMG) myasthenia gravis in Asian patients is low, thymoma and acetylcholine receptor (AchR) antibodies as well as positivity in repetitive nerve stimulation (RNS) studies all predict such generalization, a recent Singapore study has shown.