Most Read Articles
26 May 2020
Early screening for gestational diabetes does not improve the composite perinatal outcomes in obese women, reveals a study.
Audrey Abella, 26 May 2020
A novel, investigational vaginal pH regulator (VPR) – a nonhormonal, water-based, petroleum-free contraceptive vaginal gel – improved genitourinary (GU) side effects and sexual satisfaction in women who are at risk of pregnancy but are not aiming to conceive, interim findings from the phase III AMPOWER* trial show.
Pearl Toh, 21 May 2020
A levonorgestrel (LNG)-releasing intrauterine device (IUD) maintains high contraceptive efficacy up to 6 years, which is beyond the 5-year period it is currently approved for, according to data from the Mirena Extension Trial (MET) released during the ACOG 2020 Meeting.

Influenza vaccination bears no increased risk of adverse birth outcomes

19 May 2020

Influenza vaccination of pregnant women has no negative effect on the foetus, regardless of the trimester in which the shot is given, a study from Japan has found.

The study population comprised 10,330 pregnant women, among whom 3,943 (38 percent) were vaccinated and 6,387 (62 percent) were not. Vaccinated women were older and more commonly had underlying obstetric and gynaecological illnesses. On the other hand, unvaccinated women (control) frequently smoked or drank alcohol during pregnancy and were more likely to have obesity, hypertension, or foetal growth restriction as pregnancy-induced complications.

Researchers followed all women until the end of their pregnancy. They assessed the safety of vaccination in terms of adverse birth outcomes, including miscarriage, stillbirth, preterm birth, low birth weight and malformation.

The incidence of adverse birth outcomes did not significantly differ between the vaccinated and control groups (9 percent vs 10 percent, respectively). Multivariable logistic regression analysis confirmed that vaccination during pregnancy conferred no increase in the risk of adverse birth outcomes (odds ratio [OR], 0.90, 95 percent confidence interval [CI], 0.76–1.07).

Moreover, timing of vaccination did not alter the findings. Vaccination during the first or second trimester was not association with adverse birth outcomes, whereas administration of the vaccine during the third trimester even exerted a protective effect on the risk (OR, 0.70, 95 percent CI, 0.51–0.98).

Despite the presence of several limitations, the present data should help allay concerns regarding the effect of influenza vaccination on the foetus, the researchers said.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS JPOG - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
26 May 2020
Early screening for gestational diabetes does not improve the composite perinatal outcomes in obese women, reveals a study.
Audrey Abella, 26 May 2020
A novel, investigational vaginal pH regulator (VPR) – a nonhormonal, water-based, petroleum-free contraceptive vaginal gel – improved genitourinary (GU) side effects and sexual satisfaction in women who are at risk of pregnancy but are not aiming to conceive, interim findings from the phase III AMPOWER* trial show.
Pearl Toh, 21 May 2020
A levonorgestrel (LNG)-releasing intrauterine device (IUD) maintains high contraceptive efficacy up to 6 years, which is beyond the 5-year period it is currently approved for, according to data from the Mirena Extension Trial (MET) released during the ACOG 2020 Meeting.