Most Read Articles
12 Jun 2019
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
Tristan Manalac, 08 Jul 2020
Elderly coronavirus disease 2019 (COVID-19) patients with high nutritional risk appear to suffer worse outcomes, such as longer hospital stay and greater disease severity, according to a recent study.
01 Jan 2019
Twice-daily administration of a combined Lactobacillus rhamnosus and Lactobacillus helveticus probiotic in children with suspected gastroenteritis fails to prevent the development of moderate-to-severe gastroenteritis within 2 weeks after presentation, as shown in a recent study.
25 Oct 2018
Human papillomaviruses (HPVs) are commonly found in the oral cavity, but it does not appear that oral HPVs contribute to an increased risk of oesophageal cancer, according to a study.

Inflammatory bowel disease carries increased meningitis hazard

13 Jun 2020

Patients with inflammatory bowel disease (IBD) are at heightened risk of meningitis, although the number of those who develop the condition is low, a study has found.

Researchers conducted a retrospective cohort and nested case-control study using data from the Quintiles IMS Legacy PharMetrics Adjudicated Claims Database. The analysis included 50,029 patients with Crohn’s disease (CD), 59,830 patients with ulcerative colitis (UC), and 296,801 matched non-IBD comparators. The matching was based on age, sex, and region.

In the cohort, meningitis was identified in 85 CD patients, 77 UC patients, and 235 comparators. The number of those who had meningitis was 2.17 times higher in the CD group and 1.63 times higher in the UC group than in the non-IBD group. Meningitis was defined as a condition associated with an emergency department visit or hospitalization.

Conditional logistic regression models adjusted for relevant covariates showed that having at least one comorbidity conferred significantly higher odds of a meningitis claim (odds ratio [OR], 2.21, 95 percent confidence interval [CI], 1.76–2.77).

Conversely, treatment with mesalamine appeared to be protective (OR, 0.40, 95 percent CI, 0.26–0.62).

In light of the present data, the researchers recommend that physicians discuss with their patients the increase in the risk of meningitis in IBD, as well as the potential of receiving pneumococcal and meningococcal vaccinations.

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Most Read Articles
12 Jun 2019
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
Tristan Manalac, 08 Jul 2020
Elderly coronavirus disease 2019 (COVID-19) patients with high nutritional risk appear to suffer worse outcomes, such as longer hospital stay and greater disease severity, according to a recent study.
01 Jan 2019
Twice-daily administration of a combined Lactobacillus rhamnosus and Lactobacillus helveticus probiotic in children with suspected gastroenteritis fails to prevent the development of moderate-to-severe gastroenteritis within 2 weeks after presentation, as shown in a recent study.
25 Oct 2018
Human papillomaviruses (HPVs) are commonly found in the oral cavity, but it does not appear that oral HPVs contribute to an increased risk of oesophageal cancer, according to a study.