Most Read Articles
16 Jan 2021
Diagnosis of heart diseases has abruptly and significantly decreased across the globe due to the coronavirus disease 2019 (COVID-19) pandemic, especially affecting poorer countries, reveals a study.
Roshini Claire Anthony, 01 Dec 2020

An evidence-based, multifaceted intervention aimed at reducing haemodialysis catheter-related bloodstream infections (HD-CRBSIs) failed to improve this outcome, results of the REDUCCTION* trial showed.

Pearl Toh, Yesterday
While it is well known that COVID-19 illness is associated with coagulopathy, the optimal anticoagulation strategy remains elusive, and two studies presented at the ASH 2020 Congress further add to the growing debate on the appropriate anticoagulant dose for hospitalized patients with COVID-19.

Inflammatory bowel disease carries increased meningitis hazard

13 Jun 2020

Patients with inflammatory bowel disease (IBD) are at heightened risk of meningitis, although the number of those who develop the condition is low, a study has found.

Researchers conducted a retrospective cohort and nested case-control study using data from the Quintiles IMS Legacy PharMetrics Adjudicated Claims Database. The analysis included 50,029 patients with Crohn’s disease (CD), 59,830 patients with ulcerative colitis (UC), and 296,801 matched non-IBD comparators. The matching was based on age, sex, and region.

In the cohort, meningitis was identified in 85 CD patients, 77 UC patients, and 235 comparators. The number of those who had meningitis was 2.17 times higher in the CD group and 1.63 times higher in the UC group than in the non-IBD group. Meningitis was defined as a condition associated with an emergency department visit or hospitalization.

Conditional logistic regression models adjusted for relevant covariates showed that having at least one comorbidity conferred significantly higher odds of a meningitis claim (odds ratio [OR], 2.21, 95 percent confidence interval [CI], 1.76–2.77).

Conversely, treatment with mesalamine appeared to be protective (OR, 0.40, 95 percent CI, 0.26–0.62).

In light of the present data, the researchers recommend that physicians discuss with their patients the increase in the risk of meningitis in IBD, as well as the potential of receiving pneumococcal and meningococcal vaccinations.

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Most Read Articles
16 Jan 2021
Diagnosis of heart diseases has abruptly and significantly decreased across the globe due to the coronavirus disease 2019 (COVID-19) pandemic, especially affecting poorer countries, reveals a study.
Roshini Claire Anthony, 01 Dec 2020

An evidence-based, multifaceted intervention aimed at reducing haemodialysis catheter-related bloodstream infections (HD-CRBSIs) failed to improve this outcome, results of the REDUCCTION* trial showed.

Pearl Toh, Yesterday
While it is well known that COVID-19 illness is associated with coagulopathy, the optimal anticoagulation strategy remains elusive, and two studies presented at the ASH 2020 Congress further add to the growing debate on the appropriate anticoagulant dose for hospitalized patients with COVID-19.