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Inferior vena cava filters reduce mortality in patients with pulmonary embolism

15 Mar 2020

Patients with unstable pulmonary embolism who receive an inferior vena cava (IVC) filter have a significantly reduced mortality, according to a study. However, the number of unstable patients receiving an IVC filter is decreasing despite this benefit.

This retrospective cohort study was based on administrative data obtained from the National Inpatient Sample (1999–2014).

Unstable patients who received an IVC filter showed lower in-hospital all-cause mortality in each year of investigation and in all age groups. From 1999 to 2014, mortality was significantly lower with an IVC filter relative to without a filter (28.8 percent [10,140 of 35,230] vs 46.3 percent [54,018 of 116,642]; p<0.0001).

In stable patients from the same time period, mortality was comparable between patient with an IVC filter and those without a filter (5.8 percent [31,909 of 546,858] vs 6.5 percent [220,443 of 3,367,783]; p<0.0001). Among those aged >80 years, however, mortality in stable patients with an IVC filter was lower compared with those without an IVC filter (6.5 percent [7,438 of 114,457] vs 11.3 percent [64,113 of 567,348]; p<0.0001).

From 2010 to 2014, the proportion of stable patients receiving an IVC filter decreased, but still the largest number of IVC filter was inserted in this population (91.5 percent [194,502 of 212,611]).

“The largest number of IVC filters continues to be inserted in stable patients, although there is no evidence of a clinically meaningful reduced mortality with IVC filters in stable patients unless age >80 years,” the researchers noted.

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Most Read Articles
Roshini Claire Anthony, 29 May 2020

For coffee drinkers, drinking filtered coffee may be tied to a lower mortality risk, including cardiovascular disease (CVD)-related mortality, a study from Norway suggested.

Elvira Manzano, 13 Apr 2020
A gout drug that’s been around for years reduced the risk of ischaemic cardiovascular (CV) events when given at a low dose in patients who had myocardial infarction (MI) and was cost-effective, an analysis of the COLCOT* trial has shown.
27 May 2020
Glycated haemoglobin (HbA1c) levels appear to be an independent predictor of coronary artery disease in patients with ST-elevation myocardial infarction, a new study has found.
4 days ago
Familial hypercholesterolaemia (FH) does not lead to an elevated lipoprotein(a), suggest the results of a recent study. Rather, elevated lipoprotein(a) increases the chance that an individual with genetic FH will be clinically diagnosed.