Most Read Articles
Pearl Toh, 24 Oct 2019
Using e-cigarettes can lead to cellular inflammation in the lungs among healthy adults who had never smoked, even with use as short as 4 weeks, suggests a pilot study.
24 Feb 2019
Dr Ong Kian Chung, a respiratory specialist at the KC Ong Chest & Medical Clinic, Mount Elizabeth Medical Centre, Singapore spoke on the evils of tobacco use and how clinicians can help in smoking cessation.

Impaired lung function predicts atrial fibrillation

15 Oct 2019
Current guidelines recommend the use of spirometry to establish an accurate diagnosis of COPD.

The likelihood of atrial fibrillation (AF) appears to be elevated in the context of weaker pulmonary function, a recent study has shown.

The study included 9,631 participants (median age, 50 years; 48.1 percent male) in whom AF was identified using electrocardiography or self-reports of physician diagnoses, either at baseline or throughout the study period. Lung function was measured according to the forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC).

At baseline, AF was present in 59 participants, yielding a prevalence rate of 0.6 percent. This was significantly higher in the lowest vs highest quartile of FEV1% predicted (1.2 percent vs 0.3 percent; p<0.001). This translated to an elevated likelihood of developing the condition (adjusted odds ratio [OR], 5.92, 95 percent CI, 2.22–15.77).

FVC% predicted at baseline had the same effect on AF risk (adjusted OR, 5.40, 2.06–14.20).

During the follow-up period, a total of 162 new AF cases were reported, leading to an incidence rate of 1.7 percent. Kaplan-Meier curves showed that AF incidence was significantly elevated in the lowest vs highest quartile of FEV1% predicted (2.1 percent vs 1.5 percent; log-rank p=0.042). No such effect was reported for FVC% predicted.

Cox regression analyses confirmed these findings. FEV1% predicted was significantly associated with a greater risk of incident AF (adjusted hazard ratio [HR], 1.59, 1.02–2.50), while FVC% predicted was not (adjusted HR, 1.34, 0.86–2.09).

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Most Read Articles
Pearl Toh, 24 Oct 2019
Using e-cigarettes can lead to cellular inflammation in the lungs among healthy adults who had never smoked, even with use as short as 4 weeks, suggests a pilot study.
24 Feb 2019
Dr Ong Kian Chung, a respiratory specialist at the KC Ong Chest & Medical Clinic, Mount Elizabeth Medical Centre, Singapore spoke on the evils of tobacco use and how clinicians can help in smoking cessation.