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Hypertriglyceridemic waist-to-height ratio tied to incident hypertension

15 Dec 2019
Many people are hypertensive without knowing it

Incident hypertension is associated with hypertriglyceridemic waist-to-height ratio (HWHtR) and its dynamic status, according to a study of rural Chinese men. HWHtR may be used as a marker for interventions aiming to lower hypertension incidence in men.

The investigators analysed data for 10,312 nonhypertensive individuals aged 18 years from the Rural Chinese Cohort Study at baseline examination who were followed until 2014 (median follow-up, 6 years). HWHtR was defined as the combination of triglyceride level and WHtR. The probability of incident hypertension according to HWHtR and its transformation was estimated using multiple logistic regression models.

Incident hypertension occurred in 127 men and 225 women with high triglyceride level and high WHtR (HTHWH) during follow-up. After adjusting for potential confounders, the association between HTHWH and an increased probability of hypertension was significant for men (odds ratio [OR], 1.49, 95 percent confidence interval [CI], 1.01–2.20) but not for women (OR, 1.21, 95 percent CI, 0.88–1.66).

Sensitivity analyses results were robust for both men and women. Subgroup analysis by age, body mass index, and systolic and diastolic blood pressure revealed generally consistent ORs for men.

The transformation from normal triglyceride level and normal WHtR to HTHWH correlated with a higher probability of hypertension for men (OR, 4.16, 95 percent CI, 2.21–7.84) as compared with persistent normal triglyceride level and normal WHtR. For women, however, the association between change in WHtR and hypertension was not significant for almost all transformation groups.

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Most Read Articles
Pearl Toh, 20 Nov 2019
The trade-off between the risk of ischaemic vs bleeding events may be different between Asian and non-Asian patients, which warrants careful consideration when deciding on the duration of antiplatelet therapy following a percutaneous coronary intervention (PCI), according to a presentation at ESC Asia Congress 2019.
4 days ago
Participating in a long-distance skiing event may help lower the risk of hypertension, with the number of completed races showing a weak association with the risk, a study has found.
06 Sep 2019
Hypertensive adults with lower plasma zinc concentration are at increased risk of haemorrhagic stroke, especially those with higher body mass index or lower plasma copper levels, a study has found.
06 Jan 2020
Target organ damage appears to be more noticeable in patients affected by primary aldosteronism than those affected by arterial hypertension without primary aldosteronism, suggests a study, adding that specific treatment can ease such condition.