Most Read Articles
4 days ago
Use of statin appears to reduce the risks of osteoporosis, hip fractures and vertebral fracture in patients newly diagnosed with a stroke, suggests a recent study.
07 Oct 2018
Patients using long-acting opioids with immunosuppressive properties are at greater risk of developing serious infections compared with those using the nonimmunosuppressive opioid counterpart, according to a study.
5 days ago
Monitoring of adverse events is lower in ambulatory patients on amiodarone than in those on dofetilide, a recent study has found. Improving the monitoring of such agents may help reduce the risk of morbidity in this population.
Yesterday
Rather than the presence or type or urinary incontinence, increasing severity of urinary incontinence correlates with increased depression, anxiety and stress among treatment-seeking women with lower urinary tract symptoms (LUTS), suggests a study.

Human milk composition similar in breastfeeding mothers with or without coeliac disease

Kavitha G.Shekar
01 Jun 2016

Human milk (HM) macronutrient, hormone and lipid content is similar in mothers with or without coeliac disease (CD), reported a study at the 49th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) 2016 in Athens, Greece.

“HM provides important nutrients for healthy growth and development of the newborn infant,” said study author Dr. Maria Grunewald, from the Dr. von Hauner Children's Hospital, Ludwig-Maximilians-University, Munich, Germany. “Mothers who have CD and adhere to a gluten-free diet (GFD) should be encouraged to breastfeed their children as their milk presents no relevant differences in growth-related nutrients in comparison to the milk of mothers on a normal diet.”

Grunewald and team analyzed HM samples of 378 mothers from the PreventCD study conducted in five European countries. Of the total study participants, 187 had CD and 180 women adhered to the prescribed GFD. [ESPGHAN 2016, abstract N-O-031]

Macronutrients (protein, carbohydrates, and fat), peptide hormone insulin, adiponectin, fatty acids, carnitines, phosphatidylcholines and sphingomyelines levels were determined from HM samples collected at 0 to 3 months (early sampling) and 4 to 5 months (late sampling).

No difference in the concentrations of macronutrients, hormones, polar lipids, carnitines or fatty acids were found in HM of mothers with or without CD. However, the researchers reported that palmitic acid levels were lower in early HM samples of mothers with CD (22.37 versus 22.0 weight percent; p=0.001). A similar result was observed in early HM samples of women with or without GFD (22.26 vs 22.05 weight percent; p=0.007). On the other hand, late samples showed no difference in palmitic acid levels.

A possible explanation for lower palmitic acid levels in early HM samples of mothers with CD could be that GFD affects the stimulation of palmitic acid normally synthesised by carbohydrates consumed in a regular diet, said the researchers. However, this difference is low and palmitic acid, being ubiquitous, is found everywhere and supplied through other food sources, they noted.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Doctor - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
4 days ago
Use of statin appears to reduce the risks of osteoporosis, hip fractures and vertebral fracture in patients newly diagnosed with a stroke, suggests a recent study.
07 Oct 2018
Patients using long-acting opioids with immunosuppressive properties are at greater risk of developing serious infections compared with those using the nonimmunosuppressive opioid counterpart, according to a study.
5 days ago
Monitoring of adverse events is lower in ambulatory patients on amiodarone than in those on dofetilide, a recent study has found. Improving the monitoring of such agents may help reduce the risk of morbidity in this population.
Yesterday
Rather than the presence or type or urinary incontinence, increasing severity of urinary incontinence correlates with increased depression, anxiety and stress among treatment-seeking women with lower urinary tract symptoms (LUTS), suggests a study.