Most Read Articles
Roshini Claire Anthony, 03 Sep 2018

The rate of syphilis reactivity appears to be higher in individuals with dementia compared with those without the condition, a Singapore study has found.

12 Jun 2019
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
Jairia Dela Cruz, 16 Apr 2020
The odds of women passing coronavirus disease 2019 (COVID-19) to their sexual partners appear to be low, with two studies showing no evidence of the disease-causing SARS-CoV-2 virus existing in the vaginal fluids of infected patients.
Audrey Abella, 14 Aug 2018
Online HIV self-testing may provide a channel for men who have sex with men (MSM) and transgender women (TGW) to access treatment, according to a Thai study presented at AIDS 2018.

HPV virions in sperm lower chances of conception after intrauterine insemination

14 May 2019

Insemination with semen positive for human papillomavirus (HPV) virions is four times less likely to result in clinical pregnancies compared with HPV-negative sperm, a study has found.

In the study, 732 infertile couples underwent 1,753 intrauterine insemination (IUI) cycles with capacitated sperm. The outcome of biochemical and clinical pregnancy rate in IUI cycles was evaluated according to the presence of HPV virions in semen.

Researchers used quantitative polymerase chain reaction to test 3,444 separate sperm fractions, which were generated from the workup of 1,362 sperm samples, for 18 different HPV types (6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67 and 68).

The prevalence rate of HPV in sperm was 12.5 percent per IUI cycle. Sperm detected with infectious HPV virions was associated with a significantly lower rate of clinical pregnancies in comparison with HPV-negative sperm (2.9 percent vs 11.1 percent per cycle).

No pregnancies resulted from cycles that used sperm with a ratio of >0.66 HPV virions/spermatozoon (sensitivity, 100 percent; specificity, 32.5 percent).

The findings indicate that reproductive forms of the HPV virus, the virions, inhibit fertility by damaging the spermatozoa, researchers said. Therefore, detection of HPV virions in sperm should be part of routine examination and counselling of infertile couples.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Infectious Diseases - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Roshini Claire Anthony, 03 Sep 2018

The rate of syphilis reactivity appears to be higher in individuals with dementia compared with those without the condition, a Singapore study has found.

12 Jun 2019
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
Jairia Dela Cruz, 16 Apr 2020
The odds of women passing coronavirus disease 2019 (COVID-19) to their sexual partners appear to be low, with two studies showing no evidence of the disease-causing SARS-CoV-2 virus existing in the vaginal fluids of infected patients.
Audrey Abella, 14 Aug 2018
Online HIV self-testing may provide a channel for men who have sex with men (MSM) and transgender women (TGW) to access treatment, according to a Thai study presented at AIDS 2018.