Most Read Articles
Jairia Dela Cruz, 22 Apr 2020
A wristwatch-like device that monitors pulse, breathing and blood oxygen levels of the user allows physicians to provide care remotely both in hospital and nontraditional settings, and may help in the fight against the coronavirus disease 2019 (COVID-19) pandemic.
Roshini Claire Anthony, 27 May 2020

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

Stephen Padilla, 6 days ago
Herd immunity will not work in the novel coronavirus disease (COVID-19), according to an infectious disease expert who addressed over 3,600 primary care physicians (PCP) from Asia Pacific at the inaugural webcast of the MIMS COVID Conversations Series.

HPV virions in sperm lower chances of conception after intrauterine insemination

14 May 2019

Insemination with semen positive for human papillomavirus (HPV) virions is four times less likely to result in clinical pregnancies compared with HPV-negative sperm, a study has found.

In the study, 732 infertile couples underwent 1,753 intrauterine insemination (IUI) cycles with capacitated sperm. The outcome of biochemical and clinical pregnancy rate in IUI cycles was evaluated according to the presence of HPV virions in semen.

Researchers used quantitative polymerase chain reaction to test 3,444 separate sperm fractions, which were generated from the workup of 1,362 sperm samples, for 18 different HPV types (6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67 and 68).

The prevalence rate of HPV in sperm was 12.5 percent per IUI cycle. Sperm detected with infectious HPV virions was associated with a significantly lower rate of clinical pregnancies in comparison with HPV-negative sperm (2.9 percent vs 11.1 percent per cycle).

No pregnancies resulted from cycles that used sperm with a ratio of >0.66 HPV virions/spermatozoon (sensitivity, 100 percent; specificity, 32.5 percent).

The findings indicate that reproductive forms of the HPV virus, the virions, inhibit fertility by damaging the spermatozoa, researchers said. Therefore, detection of HPV virions in sperm should be part of routine examination and counselling of infertile couples.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Infectious Diseases - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Jairia Dela Cruz, 22 Apr 2020
A wristwatch-like device that monitors pulse, breathing and blood oxygen levels of the user allows physicians to provide care remotely both in hospital and nontraditional settings, and may help in the fight against the coronavirus disease 2019 (COVID-19) pandemic.
Roshini Claire Anthony, 27 May 2020

The use of a vaginal cleansing intervention prior to Caesarean delivery reduced the incidence of surgical site infections (SSIs), according to a study presented at ACOG 2020. However, the addition of intravenous (IV) azithromycin prophylaxis had no added impact on SSI rates. 

Pank Jit Sin, 21 May 2020

Persons suffering from asthma should pay particular attention to SARS-CoV-2 precautionary measures such as social distancing, regular handwashing, and wearing of masks on top of keeping their asthma in control. This is because data collected so far paints a bleaker picture for asthmatics than the normal population should they catch COVID-19.

Stephen Padilla, 6 days ago
Herd immunity will not work in the novel coronavirus disease (COVID-19), according to an infectious disease expert who addressed over 3,600 primary care physicians (PCP) from Asia Pacific at the inaugural webcast of the MIMS COVID Conversations Series.