Most Read Articles
12 Jun 2019
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
Tristan Manalac, 6 days ago
Elderly coronavirus disease 2019 (COVID-19) patients with high nutritional risk appear to suffer worse outcomes, such as longer hospital stay and greater disease severity, according to a recent study.
01 Jan 2019
Twice-daily administration of a combined Lactobacillus rhamnosus and Lactobacillus helveticus probiotic in children with suspected gastroenteritis fails to prevent the development of moderate-to-severe gastroenteritis within 2 weeks after presentation, as shown in a recent study.
25 Oct 2018
Human papillomaviruses (HPVs) are commonly found in the oral cavity, but it does not appear that oral HPVs contribute to an increased risk of oesophageal cancer, according to a study.

HPV virions in sperm lower chances of conception after intrauterine insemination

14 May 2019

Insemination with semen positive for human papillomavirus (HPV) virions is four times less likely to result in clinical pregnancies compared with HPV-negative sperm, a study has found.

In the study, 732 infertile couples underwent 1,753 intrauterine insemination (IUI) cycles with capacitated sperm. The outcome of biochemical and clinical pregnancy rate in IUI cycles was evaluated according to the presence of HPV virions in semen.

Researchers used quantitative polymerase chain reaction to test 3,444 separate sperm fractions, which were generated from the workup of 1,362 sperm samples, for 18 different HPV types (6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67 and 68).

The prevalence rate of HPV in sperm was 12.5 percent per IUI cycle. Sperm detected with infectious HPV virions was associated with a significantly lower rate of clinical pregnancies in comparison with HPV-negative sperm (2.9 percent vs 11.1 percent per cycle).

No pregnancies resulted from cycles that used sperm with a ratio of >0.66 HPV virions/spermatozoon (sensitivity, 100 percent; specificity, 32.5 percent).

The findings indicate that reproductive forms of the HPV virus, the virions, inhibit fertility by damaging the spermatozoa, researchers said. Therefore, detection of HPV virions in sperm should be part of routine examination and counselling of infertile couples.

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Most Read Articles
12 Jun 2019
Urogenital infections remain a major reason for women to visit their family physician and their subsequent referral to obstetrics and gynaecology or urology specialists. The association between abnormal vaginal microbiota and an increased risk of contracting sexually transmitted diseases (STDs), as well as an increased rate of preterm labour, indicates the need to better understand and manage urogenital health in women. Probiotics are “live microorganisms which, when administered in adequate amounts, confer a health benefit on the host”. As such, there is a sound rationale for using probiotics to maintain female vaginal and bladder health.
Tristan Manalac, 6 days ago
Elderly coronavirus disease 2019 (COVID-19) patients with high nutritional risk appear to suffer worse outcomes, such as longer hospital stay and greater disease severity, according to a recent study.
01 Jan 2019
Twice-daily administration of a combined Lactobacillus rhamnosus and Lactobacillus helveticus probiotic in children with suspected gastroenteritis fails to prevent the development of moderate-to-severe gastroenteritis within 2 weeks after presentation, as shown in a recent study.
25 Oct 2018
Human papillomaviruses (HPVs) are commonly found in the oral cavity, but it does not appear that oral HPVs contribute to an increased risk of oesophageal cancer, according to a study.