Most Read Articles
Hannah Wong, 30 Sep 2019

Taisho Pharmaceutical launches Lusefi®, an oral anti-diabetic medication for type 2 diabetes mellitus (T2DM). The medication is expected to lower blood glucose and provide adequate glycaemic control, serving as a new alternative prescription for T2DM. Lusefi, with its active ingredient luseogliflozin hydrate, is available in the form of 2.5 mg and 5 mg tablets.

07 Oct 2019
In pancreatic cancer patients undergoing chemotherapy, the presence of diabetes mellitus is associated with reduced survival and larger tumour, as well as with increased risk of death after treatment, according to a meta-analysis.
01 Apr 2019
Basal-bolus therapy using glargine 300 U/mL and insulin glulisine is superior to twice-daily injections of insulin degludec/aspart for glycaemic control without increasing the risk of hypoglycaemia, a new study suggests.

Hostility entails heightened CHD risk in postmenopausal women with diabetes

22 Sep 2019

For postmenopausal women with diabetes, being hostile may be bad for the heart, with a recent study suggesting that such personality trait contributes to an increased risk of developing coronary heart disease (CHD).

The study examined the associations between personality traits and the risk of CHD or stroke in 15,029 women aged 50–79 years with self-reported treated diabetes. A total of 1,118 incident CHD and 710 incident stroke cases were recorded over a mean follow-up of 10 years.

CHD risk was about 20-percent higher in women in the highest vs the lowest quartile of hostility (hazard ratio [HR], 1.22, 95 percent CI, 1.01–1.48). In an analysis stratified by prevalent or incident diabetes, the highest quartile of hostility carried a 34-percent heightened risk of CHD (HR, 1.34, 1.03–1.74) in women with incident diabetes.

There were no other personality traits significantly associated with stroke or CHD.

Researchers used validated scales to measure personality traits such as hostility, optimism, ambivalence over emotional expressiveness and negative emotional expressiveness. They applied multivariable Cox proportional-hazards regression models to obtain risk estimates of adjudicated CHD (nonfatal myocardial infarction and CHD death) or stroke outcomes in relation to personality traits. Demographics, depression, anthropometric variables and lifestyle factors were included in the analysis as confounders.

The present data provide a basis for targeted prevention programmes for diabetic women with a high level of hostility, according to the researchers.

Digital Edition
Asia's trusted medical magazine for healthcare professionals. Get your MIMS Endocrinology - Malaysia digital copy today!
Sign In To Download
Editor's Recommendations
Most Read Articles
Hannah Wong, 30 Sep 2019

Taisho Pharmaceutical launches Lusefi®, an oral anti-diabetic medication for type 2 diabetes mellitus (T2DM). The medication is expected to lower blood glucose and provide adequate glycaemic control, serving as a new alternative prescription for T2DM. Lusefi, with its active ingredient luseogliflozin hydrate, is available in the form of 2.5 mg and 5 mg tablets.

07 Oct 2019
In pancreatic cancer patients undergoing chemotherapy, the presence of diabetes mellitus is associated with reduced survival and larger tumour, as well as with increased risk of death after treatment, according to a meta-analysis.
01 Apr 2019
Basal-bolus therapy using glargine 300 U/mL and insulin glulisine is superior to twice-daily injections of insulin degludec/aspart for glycaemic control without increasing the risk of hypoglycaemia, a new study suggests.